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UVB irradiation.

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Bacterial (1) COX (3) Endogenous Metabolite (1) Isotope-Labeled Compounds (1) Keap1-Nrf2 (1) NF-κB (2) Reactive Oxygen Species (7) Tyrosinase (1)
By Research Areas:	Cardiovascular Disease (3) Infection (1) Inflammation/Immunology (5) Metabolic Disease (2)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1008

4-Aminobenzoic acid 1 Publications Verification PABA; Vitamin Bx; Vitamin H1; p-Aminobenzoic acid	Endogenous Metabolite Bacterial Reactive Oxygen Species	Infection
4-Aminobenzoic acid is an intermediate in the synthesis of folic acid by bacteria, plants and fungi. 4-Aminobenzoic acid has antibacterial and plant growth regulating properties .

HY-109654

Ensulizole	Reactive Oxygen Species	Metabolic Disease
Ensulizole is a sulfonated UV absorber and can intense UVB and partial UVA absorption. Ensulizole can damage the DNA through the generation of reactive oxygen species (ROS) upon UV or sunlight irradiation .

HY-N2007

Veratric acid 3,4-Dimethoxybenzoic acid	COX Reactive Oxygen Species	Cardiovascular Disease Inflammation/Immunology
Veratric acid (3,4-Dimethoxybenzoic acid) is an orally active phenolic compound derived from vegetables and fruits, has antioxidant and anti-inflammatory activities . Veratric acid also acts as a protective agent against hypertension-associated cardiovascular remodelling . Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation .

HY-116145

MHY884	Tyrosinase NF-κB	Inflammation/Immunology
MHY884 is a tyrosinase inhibitor that suppresses UVB-induced activation of NF-κB signaling pathway through the downregulation of oxidative stress. MHY884 suppresses oxidative stress in the melanoma cells and attenuates UVB-induced oxidative stress, resulting in reduced NF-κB activity in irradiated mice. MHY884 is promising for research of UVB-induced skin damage .

HY-109654R

Ensulizole (Standard)	Reactive Oxygen Species	Metabolic Disease
Ensulizole (Standard) is the analytical standard of Ensulizole. This product is intended for research and analytical applications. Ensulizole is a sulfonated UV absorber and can intense UVB and partial UVA absorption. Ensulizole can damage the DNA through the generation of reactive oxygen species (ROS) upon UV or sunlight irradiation .

HY-N2007S

Veratric acid-d6 3,4-Dimethoxybenzoic acid-d₆	Isotope-Labeled Compounds COX Reactive Oxygen Species	Cardiovascular Disease Inflammation/Immunology
Veratric acid-d₆ is deuterium labeled Veratric acid. Veratric acid (3,4-Dimethoxybenzoic acid) is an orally active phenolic compound derived from vegetables and fruits, has antioxidant[1] and anti-inflammatory activities[3]. Veratric acid also acts as a protective agent against hypertension-associated cardiovascular remodelling[2]. Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation[3].

HY-N2007R

Veratric acid (Standard)	COX Reactive Oxygen Species	Cardiovascular Disease Inflammation/Immunology
Veratric acid (Standard) is the analytical standard of Veratric acid. This product is intended for research and analytical applications. Veratric acid (3,4-Dimethoxybenzoic acid) is an orally active phenolic compound derived from vegetables and fruits, has antioxidant and anti-inflammatory activities . Veratric acid also acts as a protective agent against hypertension-associated cardiovascular remodelling . Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation .

HY-170579

Antioxidant agent-20	Reactive Oxygen Species Apoptosis NF-κB Keap1-Nrf2	Inflammation/Immunology
Antioxidant agent-20 (Compound 3d) has potent anti-inflammatory and antioxidant activity. Antioxidant agent-20 reduces reactive oxygen species (ROS) and apoptosis in a dose-dependent manner. Antioxidant agent-20 exhibits photoprotective effect against UVB-irradiated human skin keratinocytes (HaCaT) (IC₅₀=5.13 µM) via activation of Nrf2/HO-1 signaling and inhibition of NF-κB pathway .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1008

4-Aminobenzoic acid 1 Publications Verification PABA; Vitamin Bx; Vitamin H1; p-Aminobenzoic acid	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite Bacterial Reactive Oxygen Species
4-Aminobenzoic acid is an intermediate in the synthesis of folic acid by bacteria, plants and fungi. 4-Aminobenzoic acid has antibacterial and plant growth regulating properties .

HY-N2007

Veratric acid 3,4-Dimethoxybenzoic acid	Cardiovascular Disease Structural Classification other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Plants Disease Research Fields	COX Reactive Oxygen Species
Veratric acid (3,4-Dimethoxybenzoic acid) is an orally active phenolic compound derived from vegetables and fruits, has antioxidant and anti-inflammatory activities . Veratric acid also acts as a protective agent against hypertension-associated cardiovascular remodelling . Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation .

HY-N2007R

Veratric acid (Standard)	Structural Classification other families Ketones, Aldehydes, Acids Source classification Plants	COX Reactive Oxygen Species
Veratric acid (Standard) is the analytical standard of Veratric acid. This product is intended for research and analytical applications. Veratric acid (3,4-Dimethoxybenzoic acid) is an orally active phenolic compound derived from vegetables and fruits, has antioxidant and anti-inflammatory activities . Veratric acid also acts as a protective agent against hypertension-associated cardiovascular remodelling . Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation .

Cat. No.	Product Name	Chemical Structure

HY-N2007S

Veratric acid-d6
Veratric acid-d₆ is deuterium labeled Veratric acid. Veratric acid (3,4-Dimethoxybenzoic acid) is an orally active phenolic compound derived from vegetables and fruits, has antioxidant[1] and anti-inflammatory activities[3]. Veratric acid also acts as a protective agent against hypertension-associated cardiovascular remodelling[2]. Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation[3].

Veratric acid-d6

Veratric acid-d₆ is deuterium labeled Veratric acid. Veratric acid (3,4-Dimethoxybenzoic acid) is an orally active phenolic compound derived from vegetables and fruits, has antioxidant[1] and anti-inflammatory activities[3]. Veratric acid also acts as a protective agent against hypertension-associated cardiovascular remodelling[2]. Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation[3].

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