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Results for "

Warfarin

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

1

Biochemical Assay Reagents

1

Natural
Products

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-139167
    7-Hydroxywarfarin

    Warfarin RC15

    		 Drug Derivative Others
    7-Hydroxywarfarin is a Warfarin analog with anticoagulant activity .
    7-Hydroxywarfarin
  • HY-W015998S
    (R)-(+)-Warfarin-d5

    		Isotope-Labeled Compounds Others
    (R)-(+)-Warfarin-d5 is deuterium labeled (R)-(+)-Warfarin.
    (R)-(+)-Warfarin-d5
  • HY-116601
    6-Hydroxywarfarin

    		Cytochrome P450 Others
    6-Hydroxywarfarin is a metabolite of (+) -warfarin. 6-Hydroxywarfarin is a weaker vitamin K antagonist. 6-Hydroxywarfarin is metabolized by the cytochrome P450 isomer 2C9 (CYP2C9) .
    6-Hydroxywarfarin
  • HY-113958
    Difethialone

    LM-2219

    		 VD/VDR Others
    Difethialone (LM-2219) is an anticoagulant rodenticide. Difethialone shows high rodenticide activity in warfarin-sensitive and resistant strains of rats and mice. Difethialone interferes with the circulation of vitamin K in the liver, preventing the synthesis of coagulation factors, resulting in the inability of the blood to coagulate properly, ultimately causing internal bleeding and death. Difethialone can be used in studies of ecological impacts .
    Difethialone
  • HY-128720
    Diethyl oxalpropionate

    		Endogenous Metabolite Metabolic Disease
    Diethyl oxalpropionate is an intermediate for poly((R,S)-3,3-dimethylmalic acid) (PDMMLA) derivative synthesis. PDMMLA derivative can be used in synthesis of nanoparticles and study of warfarin encapsulation and controlled release .
    Diethyl oxalpropionate
  • HY-W741611
    Dehydro Warfarin

    NSC 289346

    		 Drug Metabolite Metabolic Disease
    Dehydro warfarin is a metabolite of (±)-warfarin. It is formed from (±)-warfarin by rat liver microsomes.
    Dehydro Warfarin
  • HY-W015998
    (R)-(+)-Warfarin

    		Biochemical Assay Reagents Others
    (R)-(+)-Warfarin is a biochemical assay reagent.
    (R)-(+)-Warfarin
  • HY-159002S
    Methyl-warfarin-d3

    		Isotope-Labeled Compounds Cardiovascular Disease
    Methyl-warfarin-d3 is a deuterated labeling methylated Warfarin (HY-B0687) .
    Methyl-warfarin-d3
  • HY-113958R
    Difethialone (Standard)

    		TrxR Others
    Difethialone (Standard) is the analytical standard of Difethialone. This product is intended for research and analytical applications. Difethialone (LM-2219) is an anticoagulant rodenticide. Difethialone shows high rodenticide activity in warfarin-sensitive and resistant strains of rats and mice. Difethialone interferes with the circulation of vitamin K in the liver, preventing the synthesis of coagulation factors, resulting in the inability of the blood to coagulate properly, ultimately causing internal bleeding and death. Difethialone can be used in studies of ecological impacts .
    Difethialone (Standard)
  • HY-121814A
    (R)-Acenocoumarol

    (R)-Acenocoumarin; (R)-Nicoumalone

    		 VD/VDR Cardiovascular Disease
    (R)-Acenocoumarol ((R)-Acenocoumarin; (R)-Nicoumalone) is a short-acting and orally active anticoagulant, like Warfarin (HY-B0687), works by inhibiting vitamin K epoxide reductase. (R)-Acenocoumarol has a greater in vivo anticoagulant potency than Warfarin. (R)-Acenocoumarol has a single chiral center that produces two different enantiomeric forms. (R)-Acenocoumarol has a longer plasma elimination half-life (6.6 h) and a slower plasma clearance rate (1.9 L/h) than the (S)-enantiomer, resulting in a stronger in vivo anticoagulant effect.
    (R)-Acenocoumarol
  • HY-134999
    10-Hydroxywarfarin

    		Drug Metabolite Cytochrome P450 VKOR Metabolic Disease
    10-Hydroxywarfarin, a metabolite of (R)-(+)-Warfarin (HY-W015998 ), is a CYP2C9 and vitamin K epoxide reductase complex 1 (VKOR) inhibitor with IC50s of 1.6 µM and 80 ng/mL, respectively .
    10-Hydroxywarfarin
  • HY-121535
    Levosemotiadil

    		Sodium Channel Calcium Channel Others
    Levosemotiadil, an S-isomer of semotiadil, exhibits stronger binding affinity to human serum albumin (HSA) compared to its R-isomer counterpart. This study utilized high-performance frontal analysis (HPFA) to demonstrate that levosemotiadil binds approximately three times more strongly to HSA than semotiadil. The binding parameters were evaluated using Scatchard analysis, revealing specific interactions with the diazepam binding site on HSA. The presence of diazepam decreased the binding affinity of both enantiomers, while warfarin did not alter their binding characteristics. These findings highlight levosemotiadil's potential as a Ca- and Na-channel blocker with significant binding preferences for HSA, crucial for understanding its pharmacokinetics and therapeutic effects .
    Levosemotiadil

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