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Zoniporide (Standard)

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-105064R

    CP-597396 (Standard)

    Na+/H+ Exchanger (NHE) Cardiovascular Disease
    Zoniporide (Standard) is the analytical standard of Zoniporide. This product is intended for research and analytical applications. Zoniporide (CP-597396) is a potent and selective NHE-1 inhibitor with cardioprotective activity. Zoniporide inhibits 22Na+ uptake by human NHE-1-expressing fibroblasts in a concentration-dependent manner (IC50=14 nM). Zoniporide inhibits platelet swelling in vitro with an IC50 of 0.059 μM. Zoniporide can be used in the study of cardiovascular disease[1].
    Zoniporide (Standard)
  • HY-105064DR

    CP-597396 hydrochloride hydrate (Standard)

    Na+/H+ Exchanger (NHE) Cardiovascular Disease
    Zoniporide (hydrochloride hydrate) (Standard) is the analytical standard of Zoniporide (hydrochloride hydrate). This product is intended for research and analytical applications. Zoniporide (CP-597396) hydrochloride hydrate is a potent and selective inhibitor of sodium-hydrogen exchanger type 1 (NHE-1). Zoniporide hydrochloride hydrate inhibits human NHE-1 (IC50=14 nM), and has >150-fold selectivity versus other NHE isoforms. Zoniporide hydrochloride hydrate potently inhibits ex vivo NHE-1-dependent swelling of human platelets (IC50=59 nM)[1][2].
    Zoniporide hydrochloride hydrate (Standard)

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