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Pathways Recommended: Metabolic Enzyme/Protease
Results for "

acetylated enzyme

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

3

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W048838
    Acetyl-L-lysine

    		Endogenous Metabolite Metabolic Disease
    Acetyl-L-lysine is an acetylated form of the amino acid L-lysine. Acetyl-L-lysine can participate in protein acylation processes, affecting protein functions such as stability and enzyme activity .
    Acetyl-L-lysine
  • HY-W015239
    KAT8-IN-1
    1 Publications Verification

    		 Acyltransferase Inflammation/Immunology Cancer
    KAT8-IN-1 is a lysine (K) acetyltransferase 8 (KAT8) inhibitor, with IC50s of 141 μM (KAT8), 221 μM (KAT2B), 106 μM (KAT3B), respectively. KAT8 inhibits histone acetyltransferases (HATs), and could result in disease states, such as cancer or inflammatory diseases .
    KAT8-IN-1
  • HY-W095697
    N-Acetylhistidine

    		Endogenous Metabolite Others
    N-Acetylhistidine is a histidine derivative that is the acetylated enzyme intermediate in the N-acetyltransferase reaction .
    N-Acetylhistidine
  • HY-125564
    Acetyltrialanine

    		Aminopeptidase Others
    Acetyltrialanine is a peptide containing three amino acid residues in which the N-terminal amino acid is acetylated and used as a substrate for Nα-acetyl alanine aminopeptidase in order to study the activity and properties of the enzyme. Acetyltrialanine can be used in the study of protein degradation and N-terminal regulation .
    Acetyltrialanine
  • HY-161483
    CBP/p300 ligand 3

    		Epigenetic Reader Domain Histone Acetyltransferase Neurological Disease Cancer
    CBP/p300 ligand 3 is a target protein ligand of CBPD-268 (HY-161369). CBP and p300 are two proteins with histone acetyltransferase (HAT) activity, and CBP and p300 play key roles in regulating biological processes such as gene expression, cell proliferation, differentiation and DNA repair. Through its acetyltransferase activity, CBP/p300 can acetylate histones and other proteins, thereby regulating chromatin structure and gene expression. CBP/p300 ligand 3 regulates the function of CBP/p300 by binding to a specific domain of the CBP/p300 protein (the bromine domain or HAT domain), inhibiting its enzyme activity or altering its interactions with other proteins (transcription factors). CBP/p300 ligand 3 can be used in cancer, neurodegenerative diseases and other disease models associated with abnormal CBP/p300 function .
    CBP/p300 ligand 3