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actin-related

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Arp2/3 Complex (3) Apoptosis (1) FAK (1) HIV (1) MMP (1) PI3K (1) Src (1)
By Research Areas:	Cancer (4) Infection (1) Inflammation/Immunology (1)

4

Inhibitors & Agonists

1

Recombinant Proteins

3

Antibodies

Targets Recommended: Interleukin Related Arp2/3 Complex Mas-related G-protein-coupled Receptor (MRGPR) Trk Receptor ROR NEKs Kallikrein Atg4 CGRP Receptor Atg8/LC3 ATM/ATR sFRP-1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

CK-869 1 Publications Verification	Arp2/3 Complex	Cancer
CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor, with an IC₅₀ of 7 μM.

Benproperine phosphate	Arp2/3 Complex	Inflammation/Immunology Cancer
Benproperine phosphate is an orally active, potent actin-related protein 2/3 complex subunit 2 (ARPC2) inhibitor. Benproperine phosphate attenuates the actin polymerization rate of action polymerization nucleation by impairing Arp2/3 function. Benproperine phosphate has the potential for a cough suppressant and suppresses cancer cell migration and tumor metastasis .

CK-666 5+ Cited Publications	Arp2/3 Complex HIV	Infection Cancer
CK-666 is a cell-permeable actin-related protein Arp2/3 complex inhibitor (IC₅₀=12 μM). CK-666 binds to Arp2/3 complex, stabilizes the inactive state of the complex, blocking movement of the Arp2 and Arp3 subunits into the activated filament-like (short pitch) conformation .

YH-306	FAK Src PI3K MMP Apoptosis	Cancer
YH-306 is an antitumor agent. YH-306 suppresses colorectal tumour growth and metastasis via FAK pathway. YH-306 significantly inhibits the migration and invasion of colorectal cancer cells. YH-306 potently suppresses uninhibited proliferation and induces cell apoptosis. YH-306 suppresses the activation of FAK, c-Src, paxillin, and PI3K, Rac1 and the expression of MMP2 and MMP9. YH-306 also inhibita actin-related protein (Arp2/3) complex-mediated actin polymerization .

Cat. No.	Compare	Product Name	Species	Source

	ARP3/ACTR3 Protein, Human (sf9, His-GST) actin-related protein 3; actin-like protein 3	Human	Sf9 insect cells
	ARP3/ACTR3 Proteinas, an ATPase preferentially stimulated by single-stranded DNA, crucially participates in homologous recombination repair (HRR). Independent of its ATPase function, it exhibits DNA-binding activity. SWSAP1 forms a functional complex with ZSWIM7, contributing to HRR and mutual protein stabilization. It also interacts with key players in HRR, including RAD51, RAD51B, RAD51C, RAD51D, and XRCC3, emphasizing its role in facilitating DNA repair through homologous recombination mechanisms. ARP3/ACTR3 Protein, Human (sf9, His-GST) is the recombinant human-derived ARP3/ACTR3 protein, expressed by Sf9 insect cells, with N-His, N-GST labeled tag. The total length of ARP3/ACTR3 Protein, Human (sf9, His-GST) is 417 a.a., with molecular weight of ~75.1 KDa.

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	Actin Related Protein 2 Antibody (YA2725) ACTR2; ARP2; ARP2/3 COMPLEX	WB, ICC/IF	Human, Mouse, Rat
	Actin Related Protein 2 Antibody (YA2725) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2725), targeting Actin Related Protein 2, with a predicted molecular weight of 45 kDa (observed band size: 45 kDa). Actin Related Protein 2 Antibody (YA2725) can be used for WB, ICC/IF experiment in human, mouse, rat background.

	Actin Related Protein 3 Antibody (YA1755) ACTR3; ARP3; actin-related protein 3; actin-like protein 3	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	Actin Related Protein 3 Antibody (YA1755) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1755), targeting Actin Related Protein 3, with a predicted molecular weight of 47 kDa (observed band size: 47 kDa). Actin Related Protein 3 Antibody (YA1755) can be used for WB, IHC-P, ICC/IF, FC experiment in human, mouse, rat background.

	ACTL6A Antibody (YA2684) ACTL6A; BAF53; BAF53A; INO80K; actin-like protein 6A; 53 kDa BRG1-associated factor A; actin-related protein Baf53a; ArpNbeta; BRG1-associated factor 53A; BAF53A; INO80 complex subunit K	WB, ICC/IF, IP	Human
	ACTL6A Antibody (YA2684) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2684), targeting ACTL6A, with a predicted molecular weight of 47 kDa (observed band size: 47 kDa). ACTL6A Antibody (YA2684) can be used for WB, ICC/IF, IP experiment in human background.

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