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anergy

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-107091
    Aspartyl-alanyl-diketopiperazine

    DA-DKP

    		 Others Inflammation/Immunology
    Aspartyl-alanyl-diketopiperazine (DA-DKP) is an immunomodulatory molecule generated by cleavage and cyclization from the N-terminus of human albumin and can modulate the inflammatory immune response through a molecular pathway implicated in T- lymphocyte anergy .
    Aspartyl-alanyl-diketopiperazine
  • HY-137640B
    Rp-8-Br-cAMPS

    		PKA Inflammation/Immunology
    Rp-8-Br-cAMPS is an inhibitor for PKA. Rp-8-Br-cAMPS binds to the cAMP binding site on the regulatory subunit, prevents thus the dissociation and activation of PKA. Rp-8-Br-cAMPS improves the immune functions in a retroviral-infected mouse models .
    Rp-8-Br-cAMPS
  • HY-121638
    CU-3

    		Apoptosis DGK Inflammation/Immunology Cancer
    CU-3 is the racemate of (5Z,2E)-CU-3. (5Z,2E)-CU-3 is a potent and selective inhibitor against the α-isozyme of DGK with an IC50 value of 0.6 μM, competitively inhibits the affinity of DGKα for ATP with a Km value of 0.48 mM. (5Z,2E)-CU-3 targets the catalytic region, but not the regulatory region of DGKα. (5Z,2E)-CU-3 has antitumoral and proimmunogenic effects, enhances the apoptosis of cancer cells and the activation of T cells .
    CU-3

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