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anterior pituitary

" in MedChemExpress (MCE) Product Catalog:

15

Inhibitors & Agonists

12

Peptides

3

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3

Recombinant Proteins

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-107916
    Thyrotropin
    1 Publications Verification

    TSH; Pretiron

    Others Metabolic Disease Endocrinology Cancer
    Thyrotropin is a thyroid-stimulating hormone produced by thyrotrope cells in the anterior pituitary gland. Thyrotropin regulates the endocrine function of the thyroid. Thyrotropin induces transcriptional regulation of TH-gatekeeper genes in tanycytes through the Tshr/Gαq/PKC pathway. Thyrotropin has an association of low levels with increased bone remodeling, reduced bone mass and a high fracture risk in mice. Thyrotropin is promising for research of skeletal remodeling, hyperthyroidism .
    Thyrotropin
  • HY-106373A

    ACTH TFA; Adrenocorticotrophic hormone TFA

    Androgen Receptor Metabolic Disease
    Adrenocorticotropic hormone (ACTH) TFA is a polypeptide tropic hormone produced by the anterior pituitary gland. Adrenocorticotropic hormone regulates cortisol and androgen production .
    Adrenocorticotropic hormone TFA
  • HY-107953
    Chorionic gonadotrophin
    2 Publications Verification

    hCG; Chorionic gonadotropic hormone

    Endogenous Metabolite Endocrinology Cancer
    Chorionic gonadotrophin (hCG) is a gonadotropin that can be isolated from the anterior pituitary gland. Chorionic gonadotrophin has potential applications in ovarian and follicular development .
    Chorionic gonadotrophin
  • HY-P0089A

    Growth Hormone Releasing Factor human TFA; Somatorelin (1-44) amide (human) (TFA)

    GHSR Endocrinology
    Human growth hormone-releasing factor TFA (Growth Hormone Releasing Factor human TFA) is a hypothalamic polypeptide and stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary .
    Human growth hormone-releasing factor TFA
  • HY-P4012

    Vasopressin Receptor Endocrinology
    [Asu1,6-Arg8]Vasopressin is an vasopressin agonist which potentiates cyclic AMP accumulation and ACTH release induced by corticotropin-releasing factor (CRF) in rat anterior pituitary cells in culture .
    [Asu1,6-Arg8]Vasopressin
  • HY-P3567

    Melanocortin Receptor Neurological Disease
    (p-Iodo-Phe7)-ACTH (4-10) is a adrenocorticotrophic hormone (ACTH) derivative, which is produced and secreted by the anterior pituitary gland. (p-Iodo-Phe7)-ACTH (4-10) serves as a melanocortin (MC) receptor antagonist and inhibits α-melanocyte-stimulating hormone (α-MSH)-induced excessive grooming behavior in rats .
    (p-Iodo-Phe7)-ACTH (4-10)
  • HY-106373

    ACTH; Adrenocorticotrophic hormone

    Androgen Receptor Endocrinology
    Adrenocorticotropic hormone (ACTH) is a polypeptide tropic hormone produced by the anterior pituitary gland. Adrenocorticotropic hormone regulates cortisol and androgen production .
    Adrenocorticotropic hormone
  • HY-P0089

    Growth Hormone Releasing Factor human; Somatorelin (1-44) amide (human)

    GHSR Endocrinology
    Human growth hormone-releasing factor (Growth Hormone Releasing Factor human) is a hypothalamic polypeptide and stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary .
    Human growth hormone-releasing factor
  • HY-109551

    Others Endocrinology
    Lutropin is a heterodimeric glycoprotein, a hormone produced by gonadotropic cells in the anterior pituitary gland, also known as luteinizing hormone and lutrophin. Lutropin stimulates follicular development, and can be used for researching infertility .
    Lutropin
  • HY-P4413

    Androgen Receptor Endocrinology
    (Des-Glu5)-ACTH (1-24) (human, bovine, rat) is an analogue of Adrenocorticotropic hormone (ACTH; HY-106373). ACTH is a polypeptide tropic hormone produced by the anterior pituitary gland, regulating cortisol and androgen production .
    (Des-Glu5)-ACTH (1-24) (human, bovine, rat)
  • HY-P4456

    Adrenergic Receptor Endocrinology
    (Des-His6)-ACTH (1-24) (human, bovine, rat) is an analogue of Adrenocorticotropic hormone (ACTH; HY-106373). ACTH is a polypeptide tropic hormone produced by the anterior pituitary gland, regulating cortisol and androgen production .
    (Des-His6)-ACTH (1-24) (human, bovine, rat)
  • HY-P1174

    GnRH Receptor Endocrinology
    GnRH Associated Peptide (GAP) (1-13), human is an amino acid peptide fragment derived from GnRH. GAP can increase the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in rat anterior pituitary cells. GAP also inhibit the secretion of prolactin .
    GnRH Associated Peptide (GAP) (1-13), human
  • HY-N12634

    PMSG

    Endogenous Metabolite Endocrinology
    Pregnant mare serum gonadotropin (PMSG) is a gonadotropin used to promote follicular development and ovulation in animals. PMSG exerts its regulatory effects by stimulating changes in blood hormones, gonadotropins, and cytoplasmic estradiol receptors in the anterior pituitary and hypothalamus. PMSG is commonly used in livestock to improve reproductive efficiency and can also be utilized for research on estrous cycle regulation .
    Pregnant mare serum gonadotropin
  • HY-P3685

    CRFR Endocrinology
    [Met(O)21] Corticotropin Releasing Factor, ovine is a corticotropin releasing factor isolated from ovine hypothalamic extracts. Corticotropin releasing factor (CRF) is a hypothalamic hormone, which stimulates the secretion of adrenocorticotrophic hormone (ACTH) .
    [Met(O)21] Corticotropin Releasing Factor, ovine
  • HY-132184

    5,6-EET; (±)5,6-EpETrE

    Adrenergic Receptor Calcium Channel Endocrinology
    5,6-Epoxyeicosatrienoic acid (5,6-EET; (±)5,6-EpETrE) is a fully racemic version of the enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes. In solution, 5,6-Epoxyeicosatrienoic acid degrades into 5,6-DiHET and 5,6-δ-lactone, which can be converted to 5,6-DiHET and quantified by GC-MS. In neuroendocrine cells, such as the anterior pituitary and pancreatic islets, 5,6-Epoxyeicosatrienoic acid has been implicated in the mobilization of calcium and hormone secretion. 5,6-Epoxyeicosatrienoic acid is an inhibitor of T-type voltage-gated calcium channels (Cav3) that inhibits isoforms Cav3.1, Cav3.2 (IC50=0.54 μM), and Cav3. and decreases nifedipine-resistant phenylephrine-induced vasoconstriction in isolated mouse mesenteric arteries via Cav3.2 blockade when used at a concentration of 3 μM. In addition, it is a substrate of COX-1 and COX-2.
    5,6-Epoxyeicosatrienoic acid

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