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bacterial multidrug resistance

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-158375
    MBL-IN-4

    		Beta-lactamase Bacterial Infection
    MBL-IN-4 (compound 4b) is a MBL inhibitor with the IC50 of 4.81 and 33 μM against IMP-1 and NDM-1 .
    MBL-IN-4
  • HY-149809
    AcrB-IN-1

    		Bacterial Infection
    AcrB-IN-1 (Compound H6) is a potent AcrB inhibitor. AcrB-IN-1 can be used for the reversal of bacterial multidrug resistance .
    AcrB-IN-1
  • HY-W107077
    INF55

    		Bacterial Infection
    INF55 is a NoA multidrug resistance pump inhibitor with the activity of inhibiting the NoA pump. The heterocomplex formed by INF55 combined with berberine shows the potential to combat the resistance of bacterial compounds. INF55 can enhance the antibacterial activity of berberine by reducing its efflux. The structural variants of INF55 can show different NoA inhibitory activities, thereby affecting the antibacterial effect of its corresponding heterocomplexes. Different derivatives of INF55 show similar activity in terms of antibacterial dose and effectiveness .
    INF55

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