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c-di-AMP diammonium

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-12326B
    c-di-AMP diammonium
    2 Publications Verification

    Cyclic diadenylate diammonium; Cyclic-di-AMP diammonium

    		 STING Bacterial Endogenous Metabolite Inflammation/Immunology
    c-di-AMP diammonium is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP diammonium is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP diammonium acts as a potent mucosal adjuvant stimulating both humoral and cellular responses .
    c-di-AMP diammonium

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