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calcium liberation

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Targets Recommended: Calcium Channel CaSR Calmodulin CRAC Channel

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Setipiprant ACT-129968; KYTH-105	Prostaglandin Receptor	Inflammation/Immunology Endocrinology
Setipiprant (ACT-129968) is an orally active and selective CRTH2 antagonist. Setipiprant interacts with hCRTH2 receptor with an IC₅₀ value of 6 nM. Setipiprant inhibits prostanoid receptors hDP₁ and hEP₂ with IC₅₀ values of 1290 and 2600 nM, respectively. Setipiprant can be used for the research of asthma and rhinitis .

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