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Results for "

epimastigote

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bacterial (1) Parasite (4)
By Research Areas:	Infection (5) Inflammation/Immunology (2)

5

Inhibitors & Agonists

1

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

5-Desmethylsinensetin	Bacterial	Infection Inflammation/Immunology
5-desmethylsinensetin, isolated from Artemisia princeps , possesses antiprotozoal activity. 5-desmethylsinensetin shows IC₅₀ values of 0.4 μg/mL on T. cruzi epimastigotes and 75.1 μg/mL on trypomastigotes, respectively .

Anti-Trypanosoma cruzi agent-2	Parasite	Infection Inflammation/Immunology
Anti-Trypanosoma cruzi agent-1 (Compd 3b), selective compound against NINOA trypomastigote (IC₅₀ = 0.51 µM) and INC-5 epimastigote form (IC₅₀ = 3.06 µM), posseses anti-T. gondii activity .

Anti-Trypanosoma cruzi agent-6	Parasite	Infection
Anti-Trypanosoma cruzi agent-6 (Compound 8) exhibits inhibitory activity against Trypanosoma cruzi, that inhibits the epimastigote, trypomastigote and amastigote form of T. cruzi with IC₅₀s of 24.7 µM, 1.8 µM and 1.6 µM, respectively .

RS 49676	Parasite	Infection
RS 49676 is an N-substituted imidazole compound that exhibits strong in vitro activity against endogenous amoebae (ED50 < 0.1 ng/mL), but is ineffective against exogenous amoebae (epimastigotes). In vivo, RS 49676 (100 mg/kg/d, sc, 2 times) can prolong the average survival time of mice infected with Trypanosoma cruzi to more than 11 weeks.

Anti-Trypanosoma cruzi agent-4	Parasite	Infection
Anti-Trypanosoma cruzi agent-4 (compound 5c) is an inhibitor of Trypanosoma cruzi. Anti-Trypanosoma cruzi agent-4 can be used for the research of infection .

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