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ferritin

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By Targets:	Apoptosis (1) Autophagy (1) Biochemical Assay Reagents (1) Ferroptosis (3) MDM-2/p53 (1) Transferrin Receptor (1)
By Research Areas:	Cancer (5) Metabolic Disease (1)

6

Inhibitors & Agonists

3

Recombinant Proteins

5

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

YL-939	Ferroptosis	Cancer
YL-939 is a potent ferroptosis inhibitor. YL-939 inhibits ferroptosis by targeting the PHB2/ferritin/iron axis .

Ferric maltol	Others	Metabolic Disease Cancer
Ferric maltol is an orally active monovalent iron (Fe ³⁺) complex. Ferric maltol is used in the study of iron deficiency anemia in inflammatory bowel disease .

MMRi62	Ferroptosis Apoptosis Autophagy MDM-2/p53	Cancer
MMRi62, a ferroptosis inducer targeting MDM2-MDM4 (negative regulators of tumor suppressor p53). MMRi62 shows a P53-independent pro-apoptotic activity against pancreatic ductal adenocarcinoma (PDAC) cells and induce autophagy. MMRi62 inducesferroptosis, resulting in a increase of reactive oxygen and lysosomal degradation of ferritin heavy chain (FTH1). MMRi62 also leads to proteasomal degradation of mutant p53, also inhibits orthotopic xenograft PDAC mouse model in vivo with high frequency mutation characteristics of KRAS and TP53.12 .

CGP 46700	Biochemical Assay Reagents	Others
CGP 46700 (Compound 49) is an orally active iron chelator, that exhibits high affinity for iron, removes iron from ferritin and human serum transferrin. CGP 46700 promotes iron excretion in a mouse iron overload model .

Ap44mSe	Transferrin Receptor	Cancer
Ap44mSe is a selenosemicarbazone that effectively depletes cellular Fe, resulting in transferrin receptor-1 up-regulation, ferritin down-regulation, and increased expression of the potent metastasis suppressor, N-myc downstream regulated gene-1. Ap44mSe forms redox active Cu complexes that target the lysosome to induce lysosomal membrane permeabilization .

CT-1	Ferroptosis	Cancer
CT-1 is a derivative of Cryptotanshinone (HY-N0174). CT-1 is a ferroptosis inducer. CT-1 promotes the interaction between NCOA4 and ferritin by targeting FTH1, triggering ferritinophagy-mediated ferroptosis. CT-1 has anticancer activity against triple-negative breast cancer (TNBC). CT-1 induces ferroptosis in both N2-type tumor-associated neutrophils (TANs) and TNBC cancer cells .

Species:	Human (2)
Tag:	His (2) Tag Free (1)
Source:	E. coli (3)

Cat. No.	Compare	Product Name	Species	Source

	Ferritin light chain/FTL Protein, Human (His) rHuferritin light chain/FTL, His; ferritin L subunit; ferritin light chain; FTL	Human	E. coli
	Ferritin light chain/FTL protein is pivotal in iron homeostasis, storing iron in a soluble, non-toxic form and delivering it to cells. In kidney development, FTL mediates iron uptake in capsule cells, crucial for organogenesis. Structurally, FTL, an oligomer with light and heavy subunits forming a spherical shell, facilitates iron entry through pores. Mutations in the C-terminus disrupt pore formation, impacting iron accumulation. Ferritin light chain/FTL Protein, Human (His) is the recombinant human-derived Ferritin light chain/FTL protein, expressed by E. coli , with N-6*His labeled tag. The total length of Ferritin light chain/FTL Protein, Human (His) is 175 a.a., with molecular weight of 20-25 kDa.

	Ferritin heavy chain/FTH1 Protein, Human 1 Publications Verification rHuferritin heavy chain/FTH1; ferritin heavy chain; FTH1; FTH; FTHL6; ferritin H subunit; Cell proliferation-inducing gene 15 protein	Human	E. coli
	The ferritin heavy chain/FTH1 protein is critical for maintaining iron homeostasis, storing iron in soluble form through ferroxidase activity. It promotes the oxidation of ferrous iron so that it can be deposited in the form of iron hydroxide. Ferritin heavy chain/FTH1 Protein, Human is the recombinant human-derived Ferritin heavy chain/FTH1 protein, expressed by E. coli , with tag free. The total length of Ferritin heavy chain/FTH1 Protein, Human is 183 a.a., with molecular weight of ~22.34 kDa.

	Ferritin Protein, Penaeus japonicus (His) ferritin; Penaeus japonicus; Kuruma prawn; Oxidoreductase; 1.16.3.1	Others	E. coli
	Ferritin Protein, Penaeus japonicus (His) is the recombinant Ferritin, expressed by E. coli , with His labeled tag. ,

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Cat. No.	Compare	Product Name	Application	Reactivity

	Ferritin Heavy Chain Antibody 1 Publications Verification FTH1; FTH; FTHL6; OK/SW-cl.84; PIG15; ferritin heavy chain; ferritin H subunit; Cell proliferation-inducing gene 15 protein	WB, ICC/IF	Human, Mouse, Rat, Hamster
	Ferritin Heavy Chain Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 21 kDa, targeting to Ferritin Heavy Chain. It can be used for WB,ICC/IF assays with tag free, in the background of Human, Mouse, Rat, Hamster.

	*Mitochondrial Ferritin* Antibody (YA3353)** FerH; ferritin; ferritin H subunit; ferritin; mitochondrial; Fth3; FTMT; mitochondrial; Mitochondrial ferritin; MTF	WB	Human
	Mitochondrial Ferritin Antibody (YA3353) is a non-conjugated IgG antibody, targeting Mitochondrial Ferritin, with a predicted molecular weight of 28 kDa (observed band size: 22 kDa). Mitochondrial Ferritin Antibody (YA3353) can be used for WB experiment in human background.

	Ferritin Light Chain Antibody (YA971) ferritin L chain; ferritin L subunit; ferritin light chain; ferritin light polypeptide; ferritin light polypeptide like 3; FRIL; FRIL_HUMAN; FTL; L apoferritin; LFTD; MGC71996; NBIA 3; NBIA3.	ELISA	Human
	Ferritin Light Chain Antibody (YA971) is a mouse-derived non-conjugated IgG2b antibody (Clone NO.: YA971), targeting Ferritin Light Chain. Ferritin Light Chain Antibody (YA971) can be used for ELISA experiment in human background.

	Ferritin Light Chain Antibody (YA972) ferritin L chain; ferritin L subunit; ferritin light chain; ferritin light polypeptide; ferritin light polypeptide like 3; FRIL; FRIL_HUMAN; FTL; L apoferritin; LFTD; MGC71996; NBIA 3; NBIA3.	ELISA	Human
	Ferritin Light Chain Antibody (YA972) is a mouse-derived non-conjugated IgG2a antibody (Clone NO.: YA972), targeting Ferritin Light Chain. Ferritin Light Chain Antibody (YA972) can be used for ELISA experiment in human background.

	Aconitase 1 Antibody (YA2850) ACO1; IREB1; Cytoplasmic aconitate hydratase; Aconitase; Citrate hydro-lyase; ferritin repressor protein; Iron regulatory protein 1; IRP1; Iron-responsive element-binding protein 1; IRE-BP 1	WB, ICC/IF	Human, Mouse, Rat
	Aconitase 1 Antibody (YA2850) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2850), targeting Aconitase 1, with a predicted molecular weight of 98 kDa (observed band size: 98 kDa). Aconitase 1 Antibody (YA2850) can be used for WB, ICC/IF experiment in human, mouse, rat background.

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