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Results for "

ginkgo

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (2) AMPK (2) Apoptosis (4) Autophagy (5) Bacterial (1) COX (2) Cytochrome P450 (1) Dihydroorotate Dehydrogenase (1) Endogenous Metabolite (6) ERK (2) GABA Receptor (2) iGluR (1) MMP (2) NF-κB (2) p38 MAPK (2) PKA (2) PPAR (2) Sirtuin (2) TNF Receptor (2) Wnt (2)
By Research Areas:	Cancer (2) Cardiovascular Disease (1) Infection (1) Inflammation/Immunology (7) Metabolic Disease (5) Neurological Disease (8)

Inhibitors & Agonists

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N12060

Ginkgo biloba extract	Others	Cardiovascular Disease Others
Ginkgo biloba extract a natural product isolated from Ginkgo biloba, and can be used for Atherosclerosis and cardiovascular study .

HY-B0355

Ginkgolide A 4 Publications Verification BN-52020	GABA Receptor Endogenous Metabolite	Inflammation/Immunology
Ginkgolide A (BN-52020) is an extract from in Ginkgo biloba and a g-aminobutyric acid (GABA) antagonist.

HY-N0785

Ginkgolide C 1 Publications Verification BN-52022	AMPK Sirtuin MMP Endogenous Metabolite	Neurological Disease Metabolic Disease
Ginkgolide C is a flavone isolated from Ginkgo biloba leaves, possessing multiple biological functions, such as decreasing platelet aggregation and ameliorating Alzheimer disease.

HY-N0786

Ginkgolide J	Others	Neurological Disease
Ginkgolide J is a main constituent of the non-flavone fraction of Ginkgo biloba with an IC₅₀ range of 12-54 µM, has neuroprotective and anti neuronal apoptotic ability .

HY-N4176

Ginkgolide K	Autophagy	Neurological Disease
Ginkgolide K, isolated from Ginkgo biloba, induces protective autophagy through the AMPK/mTOR/ULK1 signaling pathway. Ginkgolide K possesses neuroprotective activity .

HY-N2119

Sciadopitysin 1 Publications Verification	TNF Receptor NF-κB	Inflammation/Immunology
Sciadopitysin is a type of biflavonoids in leaves from ginkgo biloba . Sciadopitysi inhibits RANKL-induced osteoclastogenesis and bone loss by inhibiting NF-κB activation and reducing the expression of c-Fos and NFATc1 .

HY-N6964

Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside Quercetin-3-O-[2-O-(6-O-p-hydroxyl-E-coumaroyl)-D-glucosyl]-(1→2)-L-rhamnoside	Others	Metabolic Disease
Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside (Quercetin-3-O-[2-O-(6-O-p-hydroxyl-E-coumaroyl)-D-glucosyl]-(1→2)-L-rhamnoside) is one of the major antioxidants of Ginkgo biloba leaves .

HY-B0355R

Ginkgolide A (Standard) BN-52020 (Standard)	GABA Receptor Endogenous Metabolite	Inflammation/Immunology
Ginkgolide A (Standard) is the analytical standard of Ginkgolide A. This product is intended for research and analytical applications. Ginkgolide A (BN-52020) is an extract from in Ginkgo biloba and a g-aminobutyric acid (GABA) antagonist.

HY-N0785R

Ginkgolide C (Standard) BN-52022 (Standard)	AMPK Sirtuin MMP Endogenous Metabolite	Neurological Disease Metabolic Disease
Ginkgolide C (Standard) is the analytical standard of Ginkgolide C. This product is intended for research and analytical applications. Ginkgolide C is a flavone isolated from Ginkgo biloba leaves, possessing multiple biological functions, such as decreasing platelet aggregation and ameliorating Alzheimer disease.

HY-N0786R

Ginkgolide J (Standard)	Others	Neurological Disease
Ginkgolide J (Standard) is the analytical standard of Ginkgolide J. This product is intended for research and analytical applications. Ginkgolide J is a main constituent of the non-flavone fraction of Ginkgo biloba with an IC₅₀ range of 12-54 μM, has neuroprotective and anti neuronal apoptotic ability .

HY-N2119R

Sciadopitysin (Standard)	TNF Receptor NF-κB	Inflammation/Immunology
Sciadopitysin (Standard) is the analytical standard of Sciadopitysin. This product is intended for research and analytical applications. Sciadopitysin is a type of biflavonoids in leaves from ginkgo biloba . Sciadopitysi inhibits RANKL-induced osteoclastogenesis and bone loss by inhibiting NF-κB activation and reducing the expression of c-Fos and NFATc1 .

HY-N0889

Ginkgetin Maximum Cited Publications 7 Publications Verification	COX Wnt Apoptosis Autophagy	Inflammation/Immunology Cancer
Ginkgetin, a biflavone, is isolated from Ginkgo biloba leaves. Ginkgetin exhibit anti-tumor, anti-inflammatory, neuroprotective, anti-fungal activities. Ginkgetin is also a potent inhibitor of Wnt signaling, with an IC₅₀ of 5.92 μΜ .

HY-N0889R

Ginkgetin (Standard)	COX Wnt Apoptosis Autophagy	Inflammation/Immunology Cancer
Ginkgetin (Standard) is the analytical standard of Ginkgetin. This product is intended for research and analytical applications. Ginkgetin, a biflavone, is isolated from Ginkgo biloba leaves. Ginkgetin exhibit anti-tumor, anti-inflammatory, neuroprotective, anti-fungal activities. Ginkgetin is also a potent inhibitor of Wnt signaling, with an IC₅₀ of 5.92 μΜ .

HY-N0076

Bilobalide 2 Publications Verification (-)-Bilobalide	Apoptosis Autophagy Endogenous Metabolite	Neurological Disease
Bilobalide, a sesquiterpene trilactone constituent of Ginkgo biloba, inhibits the NMDA-induced efflux of choline with an IC₅₀ value of 2.3 µM. Bilobalide prevents apoptosis through activation of the PI3K/Akt pathway in SH-SY5Y cells. Exerts protective and trophic effects on neurons .

HY-N0076R

Bilobalide (Standard)	Apoptosis Autophagy Endogenous Metabolite	Neurological Disease
Bilobalide (Standard) is the analytical standard of Bilobalide. This product is intended for research and analytical applications. Bilobalide, a sesquiterpene trilactone constituent of Ginkgo biloba, inhibits the NMDA-induced efflux of choline with an IC50 value of 2.3 μM. Bilobalide prevents apoptosis through activation of the PI3K/Akt pathway in SH-SY5Y cells. Exerts protective and trophic effects on neurons .

HY-N7961

(E/Z)-Ginkgolic acid C17:2	Dihydroorotate Dehydrogenase	Others
(E/Z)-Ginkgolic acid C17:2, isolated from Ginkgo biloba, can bind with human dihydroorotate dehydrogenase (DHODH) tightly .

HY-N11978

6-Hydroxykynurenic acid 6-HKA	iGluR	Neurological Disease
6-Hydroxykynurenic acid (6-HKA) is a derivative of kynurenic acid (KYNA) and can be isolated from Ginkgo leaves. 6-Hydroxykynurenic acid is a low-affinity NMDAR antagonist (IC₅₀: 59 μM) .

HY-144513

Stigmastan-3β-ol	Bacterial	Infection
Stigmastan-3β-ol is a sterol that can be isolated from Tinospora sinensis and Ginkgo biloba L.. Stigmastan-3β-ol has antimicrobial activity .

HY-N12443

Antioxidant agent-18	Cytochrome P450	Inflammation/Immunology
Antioxidant agent-18 (compound 5) is a flavonol glycoside with antioxidant activity isolated from Ginkgo biloba. Antioxidant agent-18 scavenges DPPH radicals (IC₅₀: 15.8 μM) and reduces cytochrome c (IC₅₀: 14.7 μM).

HY-N2118

Bilobetin 2 Publications Verification	PPAR PKA Akt p38 MAPK ERK	Metabolic Disease
Bilobetin, an active component of Ginkgo biloba, can reduce blood lipids and improve the effects of insulin. Bilobetin ameliorated insulin resistance, increased the hepatic uptake and oxidation of lipids, reduced very-low-density lipoprotein triglyceride secretion and blood triglyceride levels, enhanced the expression and activity of enzymes involved in β-oxidation and attenuated the accumulation of triglycerides and their metabolites in tissues. Bilobetin also increased the phosphorylation, nuclear translocation and activity of PPARα accompanied by elevated cAMP level and PKA activity .

HY-N2118R

Bilobetin (Standard)	PPAR PKA Akt p38 MAPK ERK	Metabolic Disease
Bilobetin (Standard) is the analytical standard of Bilobetin. This product is intended for research and analytical applications. Bilobetin, an active component of Ginkgo biloba, can reduce blood lipids and improve the effects of insulin. Bilobetin ameliorated insulin resistance, increased the hepatic uptake and oxidation of lipids, reduced very-low-density lipoprotein triglyceride secretion and blood triglyceride levels, enhanced the expression and activity of enzymes involved in β-oxidation and attenuated the accumulation of triglycerides and their metabolites in tissues. Bilobetin also increased the phosphorylation, nuclear translocation and activity of PPARα accompanied by elevated cAMP level and PKA activity .

Ginkgo biloba extract	Structural Classification Natural Products Ginkgoaceae Source classification Plants Ginkgo biloba	Others
Ginkgo biloba extract a natural product isolated from Ginkgo biloba, and can be used for Atherosclerosis and cardiovascular study .

Ginkgolide A 4 Publications Verification BN-52020	Structural Classification Ginkgoaceae Classification of Application Fields Terpenoids Source classification Diterpenoids Plants Endogenous metabolite Ginkgo biloba Inflammation/Immunology Disease Research Fields	GABA Receptor Endogenous Metabolite
Ginkgolide A (BN-52020) is an extract from in Ginkgo biloba and a g-aminobutyric acid (GABA) antagonist.

Ginkgolide C 1 Publications Verification BN-52022	Structural Classification Ginkgoaceae Terpenoids Source classification Diterpenoids Plants Endogenous metabolite Ginkgo biloba	AMPK Sirtuin MMP Endogenous Metabolite
Ginkgolide C is a flavone isolated from Ginkgo biloba leaves, possessing multiple biological functions, such as decreasing platelet aggregation and ameliorating Alzheimer disease.

Ginkgolide J	Structural Classification Ginkgoaceae Terpenoids Source classification Diterpenoids Plants Ginkgo biloba	Others
Ginkgolide J is a main constituent of the non-flavone fraction of Ginkgo biloba with an IC₅₀ range of 12-54 µM, has neuroprotective and anti neuronal apoptotic ability .

Ginkgolide K	Ginkgoaceae Terpenoids Source classification Diterpenoids Plants Ginkgo biloba	Autophagy
Ginkgolide K, isolated from Ginkgo biloba, induces protective autophagy through the AMPK/mTOR/ULK1 signaling pathway. Ginkgolide K possesses neuroprotective activity .

Sciadopitysin 1 Publications Verification	Structural Classification Flavonoids Ginkgoaceae Classification of Application Fields Source classification Phenols Polyphenols Plants Biflavones Ginkgo biloba Inflammation/Immunology Disease Research Fields	TNF Receptor NF-κB
Sciadopitysin is a type of biflavonoids in leaves from ginkgo biloba . Sciadopitysi inhibits RANKL-induced osteoclastogenesis and bone loss by inhibiting NF-κB activation and reducing the expression of c-Fos and NFATc1 .

Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside Quercetin-3-O-[2-O-(6-O-p-hydroxyl-E-coumaroyl)-D-glucosyl]-(1→2)-L-rhamnoside	Flavonols Flavonoids Classification of Application Fields Ginkgoaceae Source classification Phenols Polyphenols Metabolic Disease Plants Disease Research Fields Ginkgo biloba	Others
Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside (Quercetin-3-O-[2-O-(6-O-p-hydroxyl-E-coumaroyl)-D-glucosyl]-(1→2)-L-rhamnoside) is one of the major antioxidants of Ginkgo biloba leaves .

Ginkgolide A (Standard) BN-52020 (Standard)	Structural Classification Ginkgoaceae Classification of Application Fields Terpenoids Source classification Plants Endogenous metabolite Ginkgo biloba Inflammation/Immunology Disease Research Fields	GABA Receptor Endogenous Metabolite
Ginkgolide A (Standard) is the analytical standard of Ginkgolide A. This product is intended for research and analytical applications. Ginkgolide A (BN-52020) is an extract from in Ginkgo biloba and a g-aminobutyric acid (GABA) antagonist.

Ginkgolide C (Standard) BN-52022 (Standard)	Structural Classification Ginkgoaceae Terpenoids Source classification Diterpenoids Plants Endogenous metabolite Ginkgo biloba	AMPK Sirtuin MMP Endogenous Metabolite
Ginkgolide C (Standard) is the analytical standard of Ginkgolide C. This product is intended for research and analytical applications. Ginkgolide C is a flavone isolated from Ginkgo biloba leaves, possessing multiple biological functions, such as decreasing platelet aggregation and ameliorating Alzheimer disease.

Ginkgolide J (Standard)	Structural Classification Ginkgoaceae Terpenoids Source classification Diterpenoids Plants Ginkgo biloba	Others
Ginkgolide J (Standard) is the analytical standard of Ginkgolide J. This product is intended for research and analytical applications. Ginkgolide J is a main constituent of the non-flavone fraction of Ginkgo biloba with an IC₅₀ range of 12-54 μM, has neuroprotective and anti neuronal apoptotic ability .

Sciadopitysin (Standard)	Structural Classification Flavonoids Ginkgoaceae Source classification Phenols Polyphenols Plants Biflavones Ginkgo biloba	TNF Receptor NF-κB
Sciadopitysin (Standard) is the analytical standard of Sciadopitysin. This product is intended for research and analytical applications. Sciadopitysin is a type of biflavonoids in leaves from ginkgo biloba . Sciadopitysi inhibits RANKL-induced osteoclastogenesis and bone loss by inhibiting NF-κB activation and reducing the expression of c-Fos and NFATc1 .

Ginkgetin Maximum Cited Publications 7 Publications Verification	Structural Classification Flavonoids Ginkgoaceae Classification of Application Fields Source classification Phenols Polyphenols Plants Biflavones Ginkgo biloba Disease Research Fields Cancer	COX Wnt Apoptosis Autophagy
Ginkgetin, a biflavone, is isolated from Ginkgo biloba leaves. Ginkgetin exhibit anti-tumor, anti-inflammatory, neuroprotective, anti-fungal activities. Ginkgetin is also a potent inhibitor of Wnt signaling, with an IC₅₀ of 5.92 μΜ .

Ginkgetin (Standard)	Structural Classification Flavonoids Ginkgoaceae Source classification Phenols Polyphenols Plants Biflavones Ginkgo biloba	COX Wnt Apoptosis Autophagy
Ginkgetin (Standard) is the analytical standard of Ginkgetin. This product is intended for research and analytical applications. Ginkgetin, a biflavone, is isolated from Ginkgo biloba leaves. Ginkgetin exhibit anti-tumor, anti-inflammatory, neuroprotective, anti-fungal activities. Ginkgetin is also a potent inhibitor of Wnt signaling, with an IC₅₀ of 5.92 μΜ .

Bilobalide 2 Publications Verification (-)-Bilobalide	Structural Classification Ginkgoaceae Terpenoids Sesquiterpenes Source classification Plants Endogenous metabolite Ginkgo biloba	Apoptosis Autophagy Endogenous Metabolite
Bilobalide, a sesquiterpene trilactone constituent of Ginkgo biloba, inhibits the NMDA-induced efflux of choline with an IC₅₀ value of 2.3 µM. Bilobalide prevents apoptosis through activation of the PI3K/Akt pathway in SH-SY5Y cells. Exerts protective and trophic effects on neurons .

Bilobalide (Standard)	Structural Classification Ginkgoaceae Terpenoids Sesquiterpenes Source classification Plants Endogenous metabolite Ginkgo biloba	Apoptosis Autophagy Endogenous Metabolite
Bilobalide (Standard) is the analytical standard of Bilobalide. This product is intended for research and analytical applications. Bilobalide, a sesquiterpene trilactone constituent of Ginkgo biloba, inhibits the NMDA-induced efflux of choline with an IC50 value of 2.3 μM. Bilobalide prevents apoptosis through activation of the PI3K/Akt pathway in SH-SY5Y cells. Exerts protective and trophic effects on neurons .

(E/Z)-Ginkgolic acid C17:2	Monophenols Classification of Application Fields Ginkgoaceae Ketones, Aldehydes, Acids Source classification Other Diseases Phenols Plants Disease Research Fields Ginkgo biloba	Dihydroorotate Dehydrogenase
(E/Z)-Ginkgolic acid C17:2, isolated from Ginkgo biloba, can bind with human dihydroorotate dehydrogenase (DHODH) tightly .

6-Hydroxykynurenic acid 6-HKA	Structural Classification Ginkgoaceae Ketones, Aldehydes, Acids Source classification Plants Ginkgo biloba	iGluR
6-Hydroxykynurenic acid (6-HKA) is a derivative of kynurenic acid (KYNA) and can be isolated from Ginkgo leaves. 6-Hydroxykynurenic acid is a low-affinity NMDAR antagonist (IC₅₀: 59 μM) .

Stigmastan-3β-ol	Structural Classification Ginkgoaceae Plants Ginkgo biloba Steroids	Bacterial
Stigmastan-3β-ol is a sterol that can be isolated from Tinospora sinensis and Ginkgo biloba L.. Stigmastan-3β-ol has antimicrobial activity .

Antioxidant agent-18	Structural Classification Ginkgoaceae Source classification Phenols Polyphenols Plants Ginkgo biloba	Cytochrome P450
Antioxidant agent-18 (compound 5) is a flavonol glycoside with antioxidant activity isolated from Ginkgo biloba. Antioxidant agent-18 scavenges DPPH radicals (IC₅₀: 15.8 μM) and reduces cytochrome c (IC₅₀: 14.7 μM).

Bilobetin 2 Publications Verification	Structural Classification Flavonoids Ginkgoaceae Classification of Application Fields Source classification Phenols Polyphenols Metabolic Disease Plants Biflavones Ginkgo biloba Disease Research Fields	PPAR PKA Akt p38 MAPK ERK
Bilobetin, an active component of Ginkgo biloba, can reduce blood lipids and improve the effects of insulin. Bilobetin ameliorated insulin resistance, increased the hepatic uptake and oxidation of lipids, reduced very-low-density lipoprotein triglyceride secretion and blood triglyceride levels, enhanced the expression and activity of enzymes involved in β-oxidation and attenuated the accumulation of triglycerides and their metabolites in tissues. Bilobetin also increased the phosphorylation, nuclear translocation and activity of PPARα accompanied by elevated cAMP level and PKA activity .

Bilobetin (Standard)	Structural Classification Flavonoids Ginkgoaceae Source classification Phenols Polyphenols Plants Biflavones Ginkgo biloba	PPAR PKA Akt p38 MAPK ERK
Bilobetin (Standard) is the analytical standard of Bilobetin. This product is intended for research and analytical applications. Bilobetin, an active component of Ginkgo biloba, can reduce blood lipids and improve the effects of insulin. Bilobetin ameliorated insulin resistance, increased the hepatic uptake and oxidation of lipids, reduced very-low-density lipoprotein triglyceride secretion and blood triglyceride levels, enhanced the expression and activity of enzymes involved in β-oxidation and attenuated the accumulation of triglycerides and their metabolites in tissues. Bilobetin also increased the phosphorylation, nuclear translocation and activity of PPARα accompanied by elevated cAMP level and PKA activity .

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Inhibitors & Agonists

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Natural
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