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Results for "

hepatica

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W049875
    Nitroxynil

    		Parasite Infection
    Nitroxynil, anthelmintic agent, is active against parasites in both adult and immature stages. Nitroxynil is widely used for the research of infection of Fasciola hepatica .
    Nitroxynil
  • HY-B0488
    Clorsulon

    L631529; MK401

    		 Parasite Infection
    Clorsulon (L631529; MK401) is an orally active flukicidal agent against liver flukes (Fasciola hepatica and Fasciola gigantica) infections in calves and sheep. Clorsulon is also a competitive inhibitor of both 3-phosphoglycorate and ATP andinhibits glucose utilization and acetate and propionate formation by mature Fasciola hepatica in vitro .
    Clorsulon
  • HY-B0621
    Triclabendazole
    4 Publications Verification

    CGA89317

    		 Parasite Caspase Bcl-2 Family PARP Pyroptosis Infection
    Triclabendazole is an orally active parasite inhibitor. Triclabendazole has anti-Leishmania activity and induces gasdermin E (GSDME)-dependent pyroptosis by caspase-3 activation. Triclabendazole can be used for the research of fasciola hepatica .
    Triclabendazole
  • HY-B0621R
    Triclabendazole (Standard)

    		Parasite Caspase Bcl-2 Family PARP Pyroptosis Infection
    Triclabendazole (Standard) is the analytical standard of Triclabendazole. This product is intended for research and analytical applications. Triclabendazole is an orally active parasite inhibitor. Triclabendazole has anti-Leishmania activity and induces gasdermin E (GSDME)-dependent pyroptosis by caspase-3 activation. Triclabendazole can be used for the research of fasciola hepatica .
    Triclabendazole (Standard)
  • HY-113715
    Niclofolan

    BAY 9015; Menichlopholan; Menichlofolan; Bilevon

    		 Parasite Infection
    Niclofolan (BAY 9015) is an orally active anthelmintic agent. Niclofolan can be used in the research of parasite infection .
    Niclofolan
  • HY-119893
    Diamfenetide

    		Parasite Infection
    Diamfenetide is used for the study of Fasciola hepatica infections in vitro. Diamfenetide leads to irreversible paralysis in vitro of immature and adult Fasciola hepatica .
    Diamfenetide
  • HY-119893R
    Diamfenetide (Standard)

    		Parasite Infection
    Diamfenetide (Standard) is the analytical standard of Diamfenetide. This product is intended for research and analytical applications. Diamfenetide is used for the study of Fasciola hepatica infections in vitro.?Diamfenetide?leads to irreversible paralysis in vitro of immature and adult Fasciola hepatica .
    Diamfenetide (Standard)
  • HY-W049875R
    Nitroxynil (Standard)

    		Parasite Infection
    Nitroxynil (Standard) is the analytical standard of Nitroxynil. This product is intended for research and analytical applications. Nitroxynil, anthelmintic agent, is active against parasites in both adult and immature stages. Nitroxynil is widely used for the research of infection of Fasciola hepatica .
    Nitroxynil (Standard)
  • HY-B0488R
    Clorsulon (Standard)

    		Parasite Infection
    Clorsulon (Standard) is the analytical standard of Clorsulon. This product is intended for research and analytical applications. Clorsulon (L631529; MK401) is an orally active flukicidal agent against liver flukes (Fasciola hepatica and Fasciola gigantica) infections in calves and sheep.?Clorsulon is also a competitive inhibitor of both 3-phosphoglycorate and ATP andinhibits glucose utilization and acetate and propionate formation by mature Fasciola hepatica in vitro .
    Clorsulon (Standard)
  • HY-114969
    Clioxanide

    NSC 233846; SYD 230; Tremerad

    		 Parasite Infection
    Clioxanide is a potential anti-liver fluke (Fasciola hepatica) agent. The results showed that Clioxanide showed no efficacy against 4-week-old or 19-week-old flukes at doses of 135 mg/kg or 200 mg/kg. In contrast, hexachloroethane was very effective against older flukes, reaching 100% efficacy at lower doses. The study pointed out that laboratory mice may not be suitable for screening potential compounds against liver fluke infections in ruminants such as cattle and sheep. In addition, no obvious toxic reactions were observed in mice with Clioxanide .
    Clioxanide

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