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human rhinovirus

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Enterovirus (7) Bacterial (2) DNA/RNA Synthesis (1) Interleukin Related (2) Isotope-Labeled Compounds (1) NO Synthase (1) Phosphodiesterase (PDE) (1) RSV (1) STING (1) Virus Protease (2)
By Research Areas:	Infection (9) Inflammation/Immunology (6) Neurological Disease (1)

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Recombinant Proteins

Isotope-Labeled Compounds

Targets Recommended: Enterovirus

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-112258

IMP-1088 4 Publications Verification	DNA/RNA Synthesis	Infection
IMP-1088 is a potent human N-myristoyltransferases NMT1 and NMT2 dual inhibitor with IC₅₀s of <1 nM for HsNMT1 and HsNMT2. IMP-1088 has a K_d of <210 pM for HsNMT1. IMP-1088 efficiently blocks rhinovirus replication by blocking rhinovirus virus-encoded protein (VP0) N-myristoylation. IMP-1088 protects host cells from the cytotoxic effects of viral infection .

HY-106296

WIN 54954	Enterovirus	Infection
WIN 54954 is an orally active and broad-spectrum antipicornavirus agent. WIN 54954 is effectiveness against human rhinovirus, echovirus 9 and enterovirus infections .

HY-106161

Rupintrivir 5 Publications Verification AG7088	Virus Protease Enterovirus	Infection Inflammation/Immunology
Rupintrivirvr (AG7088), an antiviral agent, is a potent, selective and irreversible inhibitor of human rhinovirus (HRV) 3C protease. Rupintrivirvr inhibits replication of a panel of 48 different HRV serotypes in H1-HeLA and MRC-5 cell protection assays, with a mean EC₅₀ of 0.023 μM. Rupintrivirvr shows immune-modulatory effect .

HY-P5836

Citrullinated LL-37 1cit	Interleukin Related Bacterial Enterovirus	Inflammation/Immunology
Citrullinated LL-37 1cit is a citrullinated LL-37 (HY-P1222) peptide. Citrullinated LL-37 1cit does not alter the antiviral effect of LL-37 toward **human rhinovirus. Citrullinated LL-37 1cit shows antibacterial** activity toward S. aureus. Citrullinated LL-37 1cit causes a reduction in the levels of IL-8, CCL5, and IL-6 mRNA induced by RV1B .

HY-106774

R-61837	Enterovirus	Infection
R-61837 is a synthetic antirhinoviral compound with significant in vitro activity. R-61837 is 10 times and 57 times more active against human rhinovirus type 9 (HRV-9) than Enviroxime and dichloroflavone (DCF), respectively, and is more active against human rhinovirus type 2 (HRV-2 ) were 5 times and 10 times higher respectively .

HY-161877

GS-7682	RSV	Infection
GS-7682 is an antiviral compound. GS-7682 has inhibitory activity against pneumoviruses and picornaviruses. GS-7682 can be used in the study of respiratory diseases such as asthma and chronic obstructive pulmonary disease .

HY-P5837

Citrullinated LL-37 2cit	Interleukin Related Enterovirus	Inflammation/Immunology
Citrullinated LL-37 2cit is a citrullinated LL-37 (HY-P1222) peptide. Citrullinated LL-37 2cit reduces LL-37 activity against HRV at 10 μg/mL and reduces the antibacterial effect of LL-37. Citrullinated LL-37 2cit causes a reduction in the levels of IL-8, CCL5, and IL-6 mRNA induced by RV1B. Citrullinated LL-37 2cit shows a moderate loss in the ability to reduce HRV-induced CCL5 secretion .

HY-P5838

Citrullinated LL-37 5cit	Bacterial	Inflammation/Immunology
Citrullinated LL-37 5cit is a citrullinated LL-37 (HY-P1222) peptide. The antiviral and antibacterial effects of Citrullinated LL-37 5cit are significantly reduced compared to native LL-37. Citrullinated LL-37 5cit is unable to reduce LPS-mediated release of TNF-α due to a lack of LPS-binding capacity .

HY-P5843

Citrullinated LL-37 4cit	Enterovirus	Infection
Citrullinated LL-37 3cit is a citrullinated LL-37 (HY-P1222) peptide. Citrullinated LL-37 3cit lacks all antiviral activity at 10 μg/mL and retains some activity against HRV at 30 μg/mL. Citrullinated LL-37 3cit reduces the immunomodulatory activity of LL-37. Citrullinated LL-37 3cit shows a moderate loss in the ability to reduce HRV-induced CCL5 secretion .

HY-168034

diABZI-4	STING	Infection Inflammation/Immunology
diABZI-4 is an oral active STING agonist with broad-spectrum antiviral activity. diABZI-4 induces the production of pro-inflammatory cytokines and lymphocyte activation by activating STING, thereby inhibiting the replication of influenza A virus (IAV), SARS-CoV-2, and human rhinovirus (HRV), with an EC₅₀ range of 11.8-199 nM .

HY-106161S1

Rupintrivir-d7 AG7088-d₇	Isotope-Labeled Compounds Enterovirus Virus Protease	Infection
Rupintrivir-d7 is a deuterated labeled Rupintrivir . Rupintrivirvr (AG7088), an antiviral agent, is a potent, selective and irreversible inhibitor of human rhinovirus (HRV) 3C protease. Rupintrivirvr inhibits replication of a panel of 48 different HRV serotypes in H1-HeLA and MRC-5 cell protection assays, with a mean EC₅₀ of 0.023 μM. Rupintrivirvr shows immune-modulatory effect .

HY-N1860

3-O-Methylquercetin	Phosphodiesterase (PDE) NO Synthase	Infection Neurological Disease Inflammation/Immunology
3-O-Methylquercetin is an inhibitor of cAMP and CGMP-phosphodiesterase (PDE) with IC₅₀ at 13.8 μM and 14.3 μM, respectively. 3-O-Methylquercetin is an inhibitor of β-secretase with an IC₅₀ of 6.5 μM. 3-O-Methylquercetin has a neuroprotective effect against neuronal death caused by oxidative damage. 3-O-Methylquercetin has strong antiviral activity against poliovirus, coxsackie virus and human rhinovirus. 3-O-Methylquercetin has anti-inflammatory and trachea-relaxing effects and can be used in the study of inflammatory diseases and asthma .

Cat. No.	Product Name	Target	Research Area

HY-P5836

Citrullinated LL-37 1cit	Interleukin Related Bacterial Enterovirus	Inflammation/Immunology
Citrullinated LL-37 1cit is a citrullinated LL-37 (HY-P1222) peptide. Citrullinated LL-37 1cit does not alter the antiviral effect of LL-37 toward **human rhinovirus. Citrullinated LL-37 1cit shows antibacterial** activity toward S. aureus. Citrullinated LL-37 1cit causes a reduction in the levels of IL-8, CCL5, and IL-6 mRNA induced by RV1B .

HY-P5837

Citrullinated LL-37 2cit	Interleukin Related Enterovirus	Inflammation/Immunology
Citrullinated LL-37 2cit is a citrullinated LL-37 (HY-P1222) peptide. Citrullinated LL-37 2cit reduces LL-37 activity against HRV at 10 μg/mL and reduces the antibacterial effect of LL-37. Citrullinated LL-37 2cit causes a reduction in the levels of IL-8, CCL5, and IL-6 mRNA induced by RV1B. Citrullinated LL-37 2cit shows a moderate loss in the ability to reduce HRV-induced CCL5 secretion .

HY-P5838

Citrullinated LL-37 5cit	Bacterial	Inflammation/Immunology
Citrullinated LL-37 5cit is a citrullinated LL-37 (HY-P1222) peptide. The antiviral and antibacterial effects of Citrullinated LL-37 5cit are significantly reduced compared to native LL-37. Citrullinated LL-37 5cit is unable to reduce LPS-mediated release of TNF-α due to a lack of LPS-binding capacity .

HY-P5843

Citrullinated LL-37 4cit	Enterovirus	Infection
Citrullinated LL-37 3cit is a citrullinated LL-37 (HY-P1222) peptide. Citrullinated LL-37 3cit lacks all antiviral activity at 10 μg/mL and retains some activity against HRV at 30 μg/mL. Citrullinated LL-37 3cit reduces the immunomodulatory activity of LL-37. Citrullinated LL-37 3cit shows a moderate loss in the ability to reduce HRV-induced CCL5 secretion .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N1860

3-O-Methylquercetin	Rhamnus nakaharai (Hayata) Hayata Structural Classification Flavonoids Classification of Application Fields Flavones Plants Rhamnaceae Inflammation/Immunology Disease Research Fields	Phosphodiesterase (PDE) NO Synthase
3-O-Methylquercetin is an inhibitor of cAMP and CGMP-phosphodiesterase (PDE) with IC₅₀ at 13.8 μM and 14.3 μM, respectively. 3-O-Methylquercetin is an inhibitor of β-secretase with an IC₅₀ of 6.5 μM. 3-O-Methylquercetin has a neuroprotective effect against neuronal death caused by oxidative damage. 3-O-Methylquercetin has strong antiviral activity against poliovirus, coxsackie virus and human rhinovirus. 3-O-Methylquercetin has anti-inflammatory and trachea-relaxing effects and can be used in the study of inflammatory diseases and asthma .

Species:	Virus (2) Human (1)
Tag:	His (1) Tag Free (1) GST (1)
Source:	HEK293 (1) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P72621

	ICAM-1/CD54 Protein, Human (HEK293, His) Intercellular Adhesion Molecule 1; ICAM-1; Major Group rhinovirus Receptor; CD54; ICAM1	Human	HEK293
	The ICAM-1/CD54 protein plays a crucial role in cell interactions, acting as a ligand for the leukocyte adhesion protein LFA-1. It promotes leukocyte transendothelial migration by promoting the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. ICAM-1/CD54 Protein, Human (HEK293, His) is the recombinant human-derived ICAM-1/CD54 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P701920

	*3C protease Protein, Human* rhinovirus 14** Genome polyprotein	Virus	E. coli
	The 3C protease protein forms an icosahedral capsid with the VP2 and VP3 proteins, with a diameter of 300 angstroms. 3C protease Protein, Human rhinovirus 14 is the recombinant Virus-derived 3C protease protein, expressed by E. coli , with tag free. The total length of 3C protease Protein, Human rhinovirus 14 is 182 a.a., .

HY-P701921

	*3C protease Protein, Human* rhinovirus 14 (GST)** Genome polyprotein	Virus	E. coli
	The 3C protease protein forms an icosahedral capsid with the VP2 and VP3 proteins, with a diameter of 300 angstroms. 3C protease Protein, Human rhinovirus 14 (GST) is the recombinant Virus-derived 3C protease protein, expressed by E. coli , with N-GST labeled tag. The total length of 3C protease Protein, Human rhinovirus 14 (GST) is 182 a.a., .

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HY-106161S1

Rupintrivir-d7
Rupintrivir-d7 is a deuterated labeled Rupintrivir . Rupintrivirvr (AG7088), an antiviral agent, is a potent, selective and irreversible inhibitor of human rhinovirus (HRV) 3C protease. Rupintrivirvr inhibits replication of a panel of 48 different HRV serotypes in H1-HeLA and MRC-5 cell protection assays, with a mean EC₅₀ of 0.023 μM. Rupintrivirvr shows immune-modulatory effect .

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human rhinovirus

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