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Results for "

miotic

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-116733
    Tafluprost ethyl ester

    AFP-175

    		 Prostaglandin Receptor Others
    Tafluprost ethyl ester (AFP-175) is a derivative of Prostaglandin F2α (PGF2α) (HY-12956). Tafluprost ethyl ester is an agonist for prostaglandin FP receptor, and exhibits miotic effect .
    Tafluprost ethyl ester
  • HY-125700
    Baogongteng A

    (-)-Bao Gong Teng A

    		 mAChR Cardiovascular Disease Neurological Disease
    Baogongteng A ((-)-Bao Gong Teng A) is an optically active tropane alkaloid with hypotensive and miotic activity, and can be isolated from the Chinese herb Erycibe obtusifolia Benth. Baogongteng A is also a muscarinic agonist. Baogongteng A can be used for cardiovascular and glaucoma research .
    Baogongteng A
  • HY-16183A
    Echothiopate chloride

    Echothiophate chloride

    		 Cholinesterase (ChE) Cardiovascular Disease
    Echothiophate (Echothiophate) chloride is a highly effective, long-lasting cholinesterase inhibitor employed as a miotic for managing glaucoma. Echothiopate chloride forms a covalent bond with the serine residue at the active site of cholinesterase through its phosphate group, rendering the enzyme permanently inactive and necessitating the synthesis of new enzymes by the cell. Given its irreversible binding to cholinesterase and the extremely slow rate of hydrolysis, the effects of echothiophate can persist for a week or longer. Echothiopate chloride is utilized as an ocular antihypertensive agent in the treatment of chronic glaucoma and, in certain cases, accommodative esotropia.
    Echothiopate chloride
  • HY-113778
    15-keto-17-phenyl trinor Prostaglandin F2α

    15-keto-17-phenyl trinor PGF2α

    		 Prostaglandin Receptor Endocrinology
    15-keto-17-phenyl trinor Prostaglandin F2α (15-keto-17-phenyl trinor PGF2α) is an F-series prostaglandin (PG) analog. The potential metabolite of 15-keto-17-phenyl trinor Prostaglandin F2α in animals is 15-keto PG. 15-keto PG can slightly reduce the intraocular pressure (1 mm Hg) in normal cynomolgus monkeys when administered at a dose of 1 μg/eye. 15-keto-17-phenyl trinor Prostaglandin F2α is a miotic agent in cats, reducing the pupil diameter by 8 mm at a dose of 5 μg/eye.
    15-keto-17-phenyl trinor Prostaglandin F2α
  • HY-116889
    15-Keto latanoprost acid

    		Drug Metabolite Others
    15-keto Latanoprost is a potential metabolite of latanoprost (HY-B0577) when administered to animals. 15-keto Latanoprost is also one of the common minor impurities found in commercial preparations of the bulk drug compound. Although much less potent that the parent compound latanoprost, 15-keto latanoprost still retains the ability to produce a small but measurable decrease (1 mm Hg) in the intraocular pressure of normal cynomolgus monkeys when administered at a dose of 1 μg/eye.1 15-keto Latanoprost is also a miotic in the normal cat eye, causing an 8 mm Hg reduction in pupillary diameter at 5 μg/eye. Again, this is not as potent as many other F-type prostaglandins; for example, prostaglandin F2α will produce this degree of miosis at a dose of less than 1 μg/eye.
    15-Keto latanoprost acid

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