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p,p'-DDD-d<sub>8</sub>

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1984S
    p,p'-DDD-d8

    4,4'-DDD-d<sub>8sub>; p,p'-Dichlorodiphenyl dichloroethane-d<sub>8sub>

    		 Drug Metabolite Apoptosis Necroptosis Insecticide Others
    p,p'-DDD-d8 is the deuterium labeled p,p'-DDD[1]. p,p'-DDD (4,4’-DDD) is an organochlorine insecticide, a major metabolite of p,p'-DDT. p,p'-DDD is an agonist at estrogen receptor α(ERα) and ERβ. p,p'-DDD increases DNA damage, apoptosis and necrosis in peripheral blood. p,p'-DDD stimulates cell proliferation in SKBR3 cells. p,p'-DDD activates the AP-1 transcription factor. p,p'-DDD decreases sleep times of barbiturates and steroids in rats .
    p,p'-DDD-d8

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