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Results for "

polyketide synthase

" in MedChemExpress (MCE) Product Catalog:

11

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2

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-116838
    TAM-16

    		Bacterial Infection
    TAM-16 is a potent and orally active polyketide synthase 13 (Pks13) inhibitor with an IC50 value of 0.32 μM. TAM-16 has promising activity against Mycobacterium tuberculosis. TAM-16 inhibits hERG cardiac ion channel .
    TAM-16
  • HY-W073762
    FBnG

    		Biochemical Assay Reagents Cancer
    FBnG is a component of non-ribosomal peptide synthetase/polyketide synthase (NRPS/PKS), which is associated with the biosynthesis of fabrubactin (FBN). FBnG can be used for synthesis of AUTAC4 as part of FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 (HY-150408) .
    FBnG
  • HY-139594
    Polyketide synthase 13-IN-1

    		Others Infection Inflammation/Immunology
    Polyketide synthase 13-IN-1 (compound 32) is a polyketide synthase 13 inhibitor .
    Polyketide synthase 13-IN-1
  • HY-139595
    Polyketide synthase 13-IN-2

    		Bacterial Infection Inflammation/Immunology
    Polyketide synthase 13-IN-2 (comp 42) is a polyketide synthase 13 inhibitor against Mycobacterium tuberculosis, with an MIC of 0.25 μg/mL .
    Polyketide synthase 13-IN-2
  • HY-139596
    Polyketide synthase 13-IN-3

    		Others Infection Inflammation/Immunology
    Polyketide synthase 13-IN-3 (compound 41) is a polyketide synthase 13 inhibitor，with a MIC of 0.0625-0.125 μg/mL against the M. tuberculosis strain H37Rv .
    Polyketide synthase 13-IN-3
  • HY-W775186
    Tolprocarb

    		Fungal Infection
    Tolprocarb is an oomyces fungicide, which has a strong inhibitory effect on rice blast fungus Magnaporthe grisea by inhibiting polyketide synthase in melanin synthesis pathway .
    Tolprocarb
  • HY-121061
    Abikoviromycin

    		Others Infection
    Abikoviromycin is an inhibitor of polyketide synthase PKS1 of C. lagenarium and can be isolated from Streptomyces .
    Abikoviromycin
  • HY-130043
    11-O-Methylpseurotin A

    		Others Inflammation/Immunology
    11-O-Methylpseurotin A is a compound of mixed polyketide synthase–nonribosomal peptide synthetase (PKS/NRPS) origin. 11-O-Methylpseurotin A selectively inhibits a Hof1 deletion strain .
    11-O-Methylpseurotin A
  • HY-117145
    Thiophene-2

    		Bacterial Infection
    Thiophene-2 (TP2) is a specific polyketide synthase 13 (Pks13) inhibitor. Thiophene-2 inhibits mycolic acid biosynthesis and rapidly leads to mycobacterial cell death. Thiophene-2 is active against Mycobacterium tuberculosis with a MIC value of 1 μM, and has potent anti-tuberculosis activity .
    Thiophene-2
  • HY-119894
    Althiomycin

    NSC 102809

    		 Antibiotic Infection
    Althiomycin is a polyketide synthase-derived thiazole antibiotic originally isolated from S. althioticus. It is active against Gram-positive bacteria, including S. aureus, S. epidermidis, and S. pyogenes (MICs=25, 25, and 3.1 μg/mL, respectively).2 Althiomycin inhibits protein synthesis in E. coli when used at concentrations of 1 and 10 μg/mL but not in isolated rabbit reticulocytes at 100 μg/mL.
    Althiomycin
  • HY-133217
    Benastatin C

    		Bacterial Infection
    Benastatin C is a polyketide synthase-derived benastatin that has been found in Streptomyces and has diverse biological activities. It inhibits glutathione S-transferase (GST; IC50=24 μg/mL for the rat liver enzyme).2 Benastatin C also inhibits the esterase activity of isolated porcine pancreatic lipase (IC50=10 μg/mL). It increases LPS- or concanavalin A-induced blastogenesis of isolated mouse spleen lymphocytes in a concentration-dependent manner.
    Benastatin C

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