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protein-ligand interactions

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amylases (1) Biochemical Assay Reagents (1) Epigenetic Reader Domain (1) Histone Acetyltransferase (1)
By Research Areas:	Cancer (2) Metabolic Disease (1) Neurological Disease (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Targets Recommended: Target Protein Ligand-Linker Conjugates E3 Ligase Ligand-Linker Conjugates PD-1/PD-L1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0910

5-Bromo-6-chloro-1H-indol-3-yl acetate	Biochemical Assay Reagents	Others
5-Bromo-6-chloro-1H-indol-3-yl acetate, a member of the indole family, is a derivative of the aromatic heterocyclic compound indole. It has been used in a variety of research settings, including studies of enzyme kinetics and protein-ligand interactions. 5-Bromo-6-chloro-1H-indol-3-yl acetate is a biomaterial or organic compound that can be used as a biomaterial or organic compound related to life science research .

HY-149008

α-Amylase-IN-3	Amylases	Metabolic Disease Cancer
α-Amylase-IN-3 (Compound 4) is a none-competitive type of α-Amylase inhibitor with an IC₅₀ value of 18.04 μM, which also has radical scavenging activities (DPPH and ABTS) with IC₅₀ values of 16.04 μM (DPPH) and 16.99 μM (ABTS), respectively. α-Amylase-IN-3 has good protein–ligand interactions profile against α-Amylase. α-Amylase-IN-3 may have pharmacological activities such as anti-oxidative, anti-inflammatory inhibitory, which is helpful for the development of diabetes and oxidative stress associated disease .

HY-161483

CBP/p300 ligand 3	Epigenetic Reader Domain Histone Acetyltransferase	Neurological Disease Cancer
CBP/p300 ligand 3 is a target protein ligand of CBPD-268 (HY-161369). CBP and p300 are two proteins with histone acetyltransferase (HAT) activity, and CBP and p300 play key roles in regulating biological processes such as gene expression, cell proliferation, differentiation and DNA repair. Through its acetyltransferase activity, CBP/p300 can acetylate histones and other proteins, thereby regulating chromatin structure and gene expression. CBP/p300 ligand 3 regulates the function of CBP/p300 by binding to a specific domain of the CBP/p300 protein (the bromine domain or HAT domain), inhibiting its enzyme activity or altering its interactions with other proteins (transcription factors). CBP/p300 ligand 3 can be used in cancer, neurodegenerative diseases and other disease models associated with abnormal CBP/p300 function .

Cat. No.	Product Name	Type

HY-D0910

5-Bromo-6-chloro-1H-indol-3-yl acetate	Biochemical Assay Reagents
5-Bromo-6-chloro-1H-indol-3-yl acetate, a member of the indole family, is a derivative of the aromatic heterocyclic compound indole. It has been used in a variety of research settings, including studies of enzyme kinetics and protein-ligand interactions. 5-Bromo-6-chloro-1H-indol-3-yl acetate is a biomaterial or organic compound that can be used as a biomaterial or organic compound related to life science research .

5-Bromo-6-chloro-1H-indol-3-yl acetate

Biochemical Assay Reagents

5-Bromo-6-chloro-1H-indol-3-yl acetate, a member of the indole family, is a derivative of the aromatic heterocyclic compound indole. It has been used in a variety of research settings, including studies of enzyme kinetics and protein-ligand interactions. 5-Bromo-6-chloro-1H-indol-3-yl acetate is a biomaterial or organic compound that can be used as a biomaterial or organic compound related to life science research .

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