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Results for "

the Linker of LTB

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

2

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-107608
    Leukotriene B4
    1 Publications Verification

    LTB4; 5(S),12(R)-DiHETE

    		 Endogenous Metabolite PROTAC Linkers Leukotriene Receptor Inflammation/Immunology Cancer
    Leukotriene B4 (LTB4) is known as one of the most potent chemoattractants and activators of leukocytes and is involved in inflammatory diseases. Leukotriene B4 is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
    Leukotriene B4
  • HY-169435
    TK-OH

    		Drug Intermediate Cancer
    TK-OH is the linker of LTB (HY-169434). TK-OH can be used for the research of cancers .
    TK-OH
  • HY-169434
    LTB

    Lon-TK-BMS-1

    		 PD-1/PD-L1 Cancer
    LTB is a prodrug formed by coupling glycolysis inhibitor with PD1/PDL1 blocker (BMS-1 (HY-19991)) by thioketal linkage. LTB can further encapsulate photosensitizer chlorine e6 (Ce6) (HY-13594) to construct a co-delivery photodynamic nanoplatform (LTB-6 NPs) by self-assembly. Pink: PD1/PDL1 blocker BMS-1, Blue: glycolysis inhibitor Lonidamine (HY-B0486), Black: linker (HY-169435) .
    LTB
  • HY-169436
    Lon-TK

    		PD-1/PD-L1
    Lon-TK is a glycolysis inhibitor + linker conjugate of LTB (HY-169434). LTB is an intelligent responsive prodrug that connects Lonidamine (Lon) (HY-B0486) and a PD-L1 inhibitor (BMS-1, HY-19991) through a thioketal linker. It significantly inhibits the glycolytic metabolism of tumor cells and blocks the PD-1/PD-L1 immune escape pathway. Lon-TK shows potential for application in photodynamic-enhanced immunotherapy research .
    Lon-TK
  • HY-107608R
    Leukotriene B4 (Standard)

    		Endogenous Metabolite PROTAC Linkers Leukotriene Receptor Inflammation/Immunology Cancer
    Leukotriene B4 (Standard) is the analytical standard of Leukotriene B4. This product is intended for research and analytical applications. Leukotriene B4 (LTB4) is known as one of the most potent chemoattractants and activators of leukocytes and is involved in inflammatory diseases. Leukotriene B4 is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
    Leukotriene B4 (Standard)

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