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Results for "

voltage sensor domain (VSD)

" in MedChemExpress (MCE) Product Catalog:

2

Inhibitors & Agonists

1

Peptides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P10817
    Corza6

    		Proton Pump Reactive Oxygen Species Metabolic Disease
    Corza6 is a potent and selective human voltage-gated proton channel (hHv1) peptide inhibitor. Corza6 binds to the external voltage sensor domain (VSD) loop in hHv1 with a Kd of ~1 nM at the natural, hyperpolarized resting membrane potential (RMP) of mammalian cells. Corza6 allows capacitation in sperm and permits sustained reactive oxygen species (ROS) production in white blood cells (WBCs) .
    Corza6
  • HY-123414
    GX-936

    PF-05196233

    		 Sodium Channel Neurological Disease
    GX-936 (PF-05196233), a potent and Nav1.7-subtype selective inhibitor, binds to the activated state of voltage-sensor domain IV (VSD4) .
    GX-936

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