2. Metabolic Enzyme/Protease
  3. Epoxide Hydrolase
  4. sEH inhibitor-2

sEH inhibitor-2 (compound 5l) is an orally active (predicted percentage absorption: 71.2-88.4%) soluble epoxide hydrolase (sEH) inhibitor, with an IC50 of 0.9 nM. sEH inhibitor-2 can maintain epoxyeicosatrienoic acids (EETs) serum level in high concentrations. sEH inhibitor-2 can be used in study of cardiovascular protection.

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sEH inhibitor-2 Chemical Structure

sEH inhibitor-2 Chemical Structure

CAS No. : 2816102-69-7

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sEH inhibitor-2 Related Antibodies

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Description

sEH inhibitor-2 (compound 5l) is an orally active (predicted percentage absorption: 71.2-88.4%) soluble epoxide hydrolase (sEH) inhibitor, with an IC50 of 0.9 nM. sEH inhibitor-2 can maintain epoxyeicosatrienoic acids (EETs) serum level in high concentrations. sEH inhibitor-2 can be used in study of cardiovascular protection[1].

IC50 & Target

sEH

0.9 nM (IC50)

Molecular Weight

398.41

Formula

C23H18N4O3
CAS No.
SMILES

O=C(C1=CC=CC=C1C(NC2=CC=C(C=C2)CN3C=C(N=N3)C4=CC=CC=C4)=O)O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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sEH inhibitor-2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

sEH inhibitor-22816102-69-7sEH inhibitor2sEH inhibitor 2Epoxide HydrolaseEETscardiovascular protectionsEH enzymemyocardial ischemia-reperfusionInhibitorinhibitorinhibit

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