Semastatin 5A.1

Cat. No.: HY-P4017: FAQs
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Semastatin 5A.1 is an anti-angiogenic 19-amino acid peptides that are derived from proteins containing type I thrombospondin motifs.

For research use only. We do not sell to patients.

Semastatin 5A.1 Chemical Structure

CAS No. : 929555-15-7

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Description

Semastatin 5A.1 is an anti-angiogenic 19-amino acid peptides that are derived from proteins containing type I thrombospondin motifs^[1].

In Vitro

Semastatin 5A.1 (0.01-40 μg/mL; 3 days) inhibits the proliferation and migration of human umbilical vein endothelial cells in vitro^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay^[1]

Cell Line:	Human umbilical vein endothelial cells (HUVECs)
Concentration:	0.01 μg/mL, 0.1 μg/mL, 1 μg/mL, 10 μg/mL, 20 μg/mL, 30 μg/mL, 40 μg/mL
Incubation Time:	3 days
Result:	Inhibited the proliferation of HUVECs in vitro.

Molecular Weight

2102.36

Formula

C₈₅H₁₄₀N₃₄O₂₅S₂

CAS No.

929555-15-7

Sequence Shortening

GPWERCTAQCGGGIQARRR

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Emmanouil D Karagiannis, et al. Anti-angiogenic peptides identified in thrombospondin type I domains. Biochem Biophys Res Commun. 2007 Jul 20;359(1):63-9. [Content Brief]

Semastatin 5A.1 Related Classifications

Cardiovascular Disease

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Semastatin 5A.1929555-15-7Othersanti-angiogenic peptideproliferationmigrationInhibitorinhibitorinhibit

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