SER-601

Cat. No.: HY-110065: FAQs
Data Sheet Handling Instructions

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SER-601 is a potent and selective peripheral cannabinoid (CB2) receptor agonist with a K_i of 6.3 nM. SER-601 has analgesic and antidiabetic properties and can be used for relevant research.

For research use only. We do not sell to patients.

SER-601 Chemical Structure

CAS No. : 1048038-90-9

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CB1 CB2

Biological Activity
Purity & Documentation
References
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Description

SER-601 is a potent and selective peripheral cannabinoid (CB2) receptor agonist with a K_i of 6.3 nM. SER-601 has analgesic and antidiabetic properties and can be used for relevant research^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
NIH3T3	IC₅₀	14 μM Compound: 2	Cytotoxicity against mouse NIH/3T3 cells assessed as cell viability after 24 hrs by neutral red uptake test Cytotoxicity against mouse NIH/3T3 cells assessed as cell viability after 24 hrs by neutral red uptake test	[PMID: 26756097]

In Vivo

SER-601 (1, 3 mg/kg, i.p.) exerts analgesic effect in a dose-dependent manner in mice formalin test^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

434.61

Formula

C₂₈H₃₈N₂O₂

CAS No.

1048038-90-9

SMILES

O=C(C(C(C1=CC(C(C)C)=CC=C12)=O)=CN2CCCCC)NC3(C[C@@H](C4)C5)C[C@@H]5C[C@@H]4C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Pasquini S, et al. Investigations on the 4-quinolone-3-carboxylic acid motif. 2. Synthesis and structure-activity relationship of potent and selective cannabinoid-2 receptor agonists endowed with analgesic activity in vivo. J Med Chem. 2008 Aug 28;51(16):5075-84. [Content Brief]

SER-601 Related Classifications

Neurological Disease

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SER-6011048038-90-9SER601SER 601Cannabinoid ReceptorCB2 receptoranalgesicantidiabeticInhibitorinhibitorinhibit

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