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  3. Isotope-Labeled Compounds
  4. Serotonin-d4 hydrochloride

Serotonin-d4 hydrochloride  (Synonyms: 5-Hydroxytryptamine-d4 hydrochloride; 5-HT-d4 hydrochloride)

Cat. No.: HY-B1473S
Handling Instructions

Molarity Calculator

Serotonin-d4 (5-Hydroxytryptamine-d4) hydrochlorideis the deuterium labeledSerotonin (hydrochloride)(HY-B1473). Serotonin (5-Hydroxytryptamine) hydrochloride is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin hydrochloride is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM.

For research use only. We do not sell to patients.

Serotonin-d<sub>4</sub> hydrochloride Chemical Structure

Serotonin-d4 hydrochloride Chemical Structure

CAS No. : 2469263-61-2

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Serotonin-d4 hydrochloride Related Antibodies

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Description

Serotonin-d4 (5-Hydroxytryptamine-d4) hydrochlorideis the deuterium labeledSerotonin (hydrochloride)(HY-B1473)[1]. Serotonin (5-Hydroxytryptamine) hydrochloride is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin hydrochloride is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Serotonin-d4 hydrochloride Related Antibodies
Molecular Weight

216.70

Formula

C10H9D4ClN2O
CAS No.
Unlabeled CAS

153-98-0
Appearance

Solid

SMILES

OC1=CC2=C(NC=C2C([2H])([2H])C([2H])([2H])N)C=C1.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 200 mg/mL (922.93 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.6147 mL 23.0734 mL 46.1467 mL
5 mM 0.9229 mL 4.6147 mL 9.2293 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 4.6147 mL 23.0734 mL 46.1467 mL 115.3669 mL
5 mM 0.9229 mL 4.6147 mL 9.2293 mL 23.0734 mL
10 mM 0.4615 mL 2.3073 mL 4.6147 mL 11.5367 mL
15 mM 0.3076 mL 1.5382 mL 3.0764 mL 7.6911 mL
20 mM 0.2307 mL 1.1537 mL 2.3073 mL 5.7683 mL
25 mM 0.1846 mL 0.9229 mL 1.8459 mL 4.6147 mL
30 mM 0.1538 mL 0.7691 mL 1.5382 mL 3.8456 mL
40 mM 0.1154 mL 0.5768 mL 1.1537 mL 2.8842 mL
50 mM 0.0923 mL 0.4615 mL 0.9229 mL 2.3073 mL
60 mM 0.0769 mL 0.3846 mL 0.7691 mL 1.9228 mL
80 mM 0.0577 mL 0.2884 mL 0.5768 mL 1.4421 mL
100 mM 0.0461 mL 0.2307 mL 0.4615 mL 1.1537 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Serotonin-d4 hydrochloride Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Serotonin-d42469263-61-25-Hydroxytryptamine-d45-HT-d4Isotope-Labeled CompoundsInhibitorinhibitorinhibit

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