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  4. SF-1 antagonist-1

SF-1 antagonist-1 (compound 11) is a antagonist of steroidogenic factor 1 (SF-1). SF-1 antagonist-1 affects SF-1 transcriptional activity with an EC50 value of ＜200 nM. SF-1 antagonist-1 inhibits the proliferation of Rat Leydig tumor cells. SF-1 antagonist-1 can be used for the research of cancer.

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SF-1 antagonist-1 Chemical Structure

SF-1 antagonist-1 Chemical Structure

CAS No. : 2842079-86-9

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SF-1 antagonist-1 Related Antibodies

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Description

SF-1 antagonist-1 (compound 11) is a antagonist of steroidogenic factor 1 (SF-1). SF-1 antagonist-1 affects SF-1 transcriptional activity with an EC50 value of ＜200 nM. SF-1 antagonist-1 inhibits the proliferation of Rat Leydig tumor cells. SF-1 antagonist-1 can be used for the research of cancer[1].

In Vitro

SF-1 antagonist-1 (0-20 μM) affects SF-1 transcriptional activity with an EC50 value of ＜200 nM[1].
SF-1 antagonist-1 (0-20 μM; 48 h) affects proliferation of R2C cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

SF-1 antagonist-1 Related Antibodies

Cell Proliferation Assay[1]

Cell Line: Rat Leydig tumor cell line, R2C
Concentration: 0-20 μM
Incubation Time: 48 h
Result: Inhibited proliferation of R2C cells with an EC50 value of ＜200 nM.
Molecular Weight

490.41

Formula

C22H18F4N6O3
CAS No.
SMILES

FC(F)(F)C(C=C1)=CC=C1NC2=NN(C)C3=C2N=CN(CC(NC4=CC=C(OC)C(F)=C4)=O)C3=O
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Purity & Documentation
References
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SF-1 antagonist-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SF-1 antagonist-12842079-86-9Otherspyrazolopyrimidinone derivativepreparationanti-proliferationR2CInhibitorinhibitorinhibit

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SF-1 antagonist-1
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