2. Metabolic Enzyme/Protease
  3. SGK
  4. SGK1-IN-5

SGK1-IN-5 (Compound 1) is an inhibitor for serum and glucocorticoid regulated kinase SGK 1 with an IC50 of 3 nM. SGK1-IN-5 inhibits SGK-1 dependent phosphorylation of GSK3β in U2OS cells with an IC50 of 1.4 μM. SGK1-IN-5 can be used in research about osteoarthritis or rheumatism.

For research use only. We do not sell to patients.

SGK1-IN-5 Chemical Structure

SGK1-IN-5 Chemical Structure

CAS No. : 1426214-51-8

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SGK1-IN-5 Related Antibodies

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Description

SGK1-IN-5 (Compound 1) is an inhibitor for serum and glucocorticoid regulated kinase SGK 1 with an IC50 of 3 nM. SGK1-IN-5 inhibits SGK-1 dependent phosphorylation of GSK3β in U2OS cells with an IC50 of 1.4 μM. SGK1-IN-5 can be used in research about osteoarthritis or rheumatism[1].

Molecular Weight

435.29

Formula

C17H12Cl2N6O2S
CAS No.
SMILES

O=S(C1=CC=CC(Cl)=C1Cl)(NC2=CC=C(C3=CN=C4C(NN=C4N)=N3)C=C2)=O
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
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SGK1-IN-5 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SGK1-IN-51426214-51-8SGKSerum-glucocorticoid regulated kinaseSerum and glucocorticoid-regulated kinaseOsteoarthritisrheumatismdegenerative joint disorderInhibitorinhibitorinhibit

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