2. Anti-infection Metabolic Enzyme/Protease
  3. Parasite Mitochondrial Metabolism
  4. Sitamaquine tosylate

Sitamaquine tosylate  (Synonyms: WR 6026 tosylate)

Cat. No.: HY-19688B
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Sitamaquine (WR6026) tosylate, an orally active 8-aminoquinoline analog, is an antileishmanial agent. Sitamaquine tosylate inhibits mitochondrial complex II (succinate dehydrogenase). Sitamaquine tosylate is a lipophilic weak base that rapidly accumulates in acidic compartments of Leishmania spp., mainly in acidocalcisomes.

For research use only. We do not sell to patients.

Sitamaquine tosylate Chemical Structure

Sitamaquine tosylate Chemical Structure

CAS No. : 1019640-33-5

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Based on 1 publication(s) in Google Scholar

Other Forms of Sitamaquine tosylate:

Sitamaquine tosylate Related Antibodies

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

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Description

Sitamaquine (WR6026) tosylate, an orally active 8-aminoquinoline analog, is an antileishmanial agent. Sitamaquine tosylate inhibits mitochondrial complex II (succinate dehydrogenase). Sitamaquine tosylate is a lipophilic weak base that rapidly accumulates in acidic compartments of Leishmania spp., mainly in acidocalcisomes[1][2].

IC50 & Target

Leishmania

 

Clinical Trial
Molecular Weight

515.71

Formula

C28H41N3O4S
CAS No.
SMILES

CC1=CC=NC2=C(NCCCCCCN(CC)CC)C=C(OC)C=C12.O=S(C3=CC=C(C)C=C3)(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Sitamaquine tosylate Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sitamaquine1019640-33-5WR 6026WR6026WR-6026ParasiteMitochondrial Metabolism8-aminoquinolineanalogantileishmaniallipophilicacidocalcisomesInhibitorinhibitorinhibit

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