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  3. SKF 106760

SKF 106760 is a potent platelet fibrin receptor (glycoprotein IIb/IIIa) antagonist with significant antiplatelet and antithrombotic activities. SKF 106760 inhibits platelet aggregation in dogs in vitro and prevents thrombus formation in stenotic carotid arteries. SKF 106760 has also shown elimination effects against aspirin-resistant thrombi that develop in the setting of high-grade stenosis.

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SKF 106760 Chemical Structure

SKF 106760 Chemical Structure

CAS No. : 126053-71-2

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Description

SKF 106760 is a potent platelet fibrin receptor (glycoprotein IIb/IIIa) antagonist with significant antiplatelet and antithrombotic activities. SKF 106760 inhibits platelet aggregation in dogs in vitro and prevents thrombus formation in stenotic carotid arteries. SKF 106760 has also shown elimination effects against aspirin-resistant thrombi that develop in the setting of high-grade stenosis[1].

Molecular Weight

633.74

Formula

C23H39N9O8S2

CAS No.
Sequence

Ac-Cys-{(NMe)Arg}-Gly-Asp-{Pen}-NH2 (Disulfidebridge:Cys1-Pen5)

Sequence Shortening

Ac-C-{(NMe)Arg}-GD-{Pen}-NH2 (Disulfidebridge:Cys1-Pen5)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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SKF 106760 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
SKF 106760
Cat. No.:
HY-P3082
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