2. GPCR/G Protein
  3. LPL Receptor
  4. SLF80821178 hydrochloride

SLF80821178 hydrochloride is an orally active inhibitor for sphingosine-1-phosphate transporter (Spns2), that inhibits the sphingosine-1-phosphate (S1P) release in HeLa with an IC50 of 51 nM. SLF80821178 hydrochloride reduces the circulating lymphocyte without affecting plasma S1P levels in mice.

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SLF80821178 hydrochloride Chemical Structure

SLF80821178 hydrochloride Chemical Structure

CAS No. : 2764877-62-3

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SLF80821178 hydrochloride Related Antibodies

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Description

SLF80821178 hydrochloride is an orally active inhibitor for sphingosine-1-phosphate transporter (Spns2), that inhibits the sphingosine-1-phosphate (S1P) release in HeLa with an IC50 of 51 nM. SLF80821178 hydrochloride reduces the circulating lymphocyte without affecting plasma S1P levels in mice[1].

Molecular Weight

381.98

Formula

C21H36ClN3O
CAS No.
SMILES

O=C(N1CCNCC1)NC2=CC=C(CCCCCCCCCC)C=C2.Cl
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SLF80821178 hydrochloride Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SLF808211782764877-62-3SLF 80821178SLF-80821178LPL ReceptorLysophospholipid ReceptorC54BL/6J mouseorally activeInhibitorinhibitorinhibit

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