2. Epigenetics
  3. Epigenetic Reader Domain
  4. SMARCA2-IN-6

SMARCA2-IN-6 is a SMARCA2 (also known as BRM) inhibitor, with IC50s less than 5 nM for SMARCA2 and SMARCA4. SMARCA2-IN-6 inhibits KRT80 gene expression in H1299 cells (IC50: 26 nM). SMARCA2-IN-6 inhibits proliferation in BRG1-mutant SKMEL5 cells (IC50: 13 nM).

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SMARCA2-IN-6 Chemical Structure

SMARCA2-IN-6 Chemical Structure

CAS No. : 2270875-79-9

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SMARCA2-IN-6 Related Antibodies

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Description

SMARCA2-IN-6 is a SMARCA2 (also known as BRM) inhibitor, with IC50s less than 5 nM for SMARCA2 and SMARCA4. SMARCA2-IN-6 inhibits KRT80 gene expression in H1299 cells (IC50: 26 nM). SMARCA2-IN-6 inhibits proliferation in BRG1-mutant SKMEL5 cells (IC50: 13 nM)[1].

Molecular Weight

319.72

Formula

C10H8ClF2N5OS
CAS No.
SMILES

O=C(NC1=CC(C(F)F)=NS1)NC2=CC(Cl)=NC=C2N
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SMARCA2-IN-6 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SMARCA2-IN-62270875-79-9Epigenetic Reader DomainInhibitorinhibitorinhibit

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