2. Stem Cell/Wnt
  3. Smo Hedgehog
  4. SMO-IN-3

SMO-IN-3 (compound 12a) is a potent smoothened (SMO) inhibitor with an IC50 value of 34.09 nM for hedgehog (Hh) signaling pathway. SMO-IN-3 has antiproliferative activity against human medulloblastoma cell line Daoy. Anticancer activity.

For research use only. We do not sell to patients.

SMO-IN-3 Chemical Structure

SMO-IN-3 Chemical Structure

CAS No. : 2376914-71-3

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SMO-IN-3 Related Antibodies

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Description

SMO-IN-3 (compound 12a) is a potent smoothened (SMO) inhibitor with an IC50 value of 34.09 nM for hedgehog (Hh) signaling pathway. SMO-IN-3 has antiproliferative activity against human medulloblastoma cell line Daoy. Anticancer activity[1].

IC50 & Target

IC50: 34.09 nM (Hh)[1]
In Vitro

SMO-IN-3 (compound 12a) has antiproliferative activity against human medulloblastoma cell line Daoy with an IC50 of 0.48 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

SMO-IN-3 Related Antibodies
Molecular Weight

499.50

Formula

C27H25F4N3O2
CAS No.
SMILES

O=C(N(C)C1CCN(C(C2=CC=CC=C2NC3=CC=CC=C3)=O)CC1)C4=CC=C(F)C=C4C(F)(F)F
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SMO-IN-3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SMO-IN-32376914-71-3SmoHedgehogSmoothenedanticancermedulloblastomaDaoyInhibitorinhibitorinhibit

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