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  4. Sodium metabisulfite

Sodium metabisulfite can be used as an excipient, such as antibacterial agent, preservative, antioxidant. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs.

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Sodium metabisulfite Chemical Structure

Sodium metabisulfite Chemical Structure

CAS No. : 7681-57-4

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Based on 1 publication(s) in Google Scholar

Other Forms of Sodium metabisulfite:

Sodium metabisulfite Related Antibodies

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Description

Sodium metabisulfite can be used as an excipient, such as antibacterial agent, preservative, antioxidant. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].

Molecular Weight

190.11

Formula

Na2O5S2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[Na].O=S(O)S(=O)(=O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature, keep dry and cool

In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (526.01 mM; Need ultrasonic)

DMSO : 2 mg/mL (10.52 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.2601 mL 26.3006 mL 52.6011 mL
5 mM 1.0520 mL 5.2601 mL 10.5202 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥99.0%

SDS (614 KB)

COA (248 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 5.2601 mL 26.3006 mL 52.6011 mL 131.5028 mL
5 mM 1.0520 mL 5.2601 mL 10.5202 mL 26.3006 mL
10 mM 0.5260 mL 2.6301 mL 5.2601 mL 13.1503 mL
H2O 15 mM 0.3507 mL 1.7534 mL 3.5067 mL 8.7669 mL
20 mM 0.2630 mL 1.3150 mL 2.6301 mL 6.5751 mL
25 mM 0.2104 mL 1.0520 mL 2.1040 mL 5.2601 mL
30 mM 0.1753 mL 0.8767 mL 1.7534 mL 4.3834 mL
40 mM 0.1315 mL 0.6575 mL 1.3150 mL 3.2876 mL
50 mM 0.1052 mL 0.5260 mL 1.0520 mL 2.6301 mL
60 mM 0.0877 mL 0.4383 mL 0.8767 mL 2.1917 mL
80 mM 0.0658 mL 0.3288 mL 0.6575 mL 1.6438 mL
100 mM 0.0526 mL 0.2630 mL 0.5260 mL 1.3150 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Sodium metabisulfite Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sodium metabisulfite7681-57-4Biochemical Assay Reagentspharmaceutical excipientpharmaceutical auxiliariepharmaceutical ingredientsinactive ingredientsstabilitysolubilityprocessabilityabsorptiondistributionmetabolismand elimination (ADME)Inhibitorinhibitorinhibit

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