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Sodium pyrophosphate  (Synonyms: Disodium pyrophosphate; Sodium acid pyrophosphate; SAPP)

Cat. No.: HY-W105970 Purity: ≥98.0%
SDS COA Handling Instructions

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Sodium pyrophosphate (Disodium pyrophosphate), a food additive, is an inorganic compound. Sodium pyrophosphate has potential hematotoxic and immunotoxic effects.

For research use only. We do not sell to patients.

Sodium pyrophosphate Chemical Structure

Sodium pyrophosphate Chemical Structure

CAS No. : 7758-16-9

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Based on 1 publication(s) in Google Scholar

Sodium pyrophosphate Related Antibodies

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Description

Sodium pyrophosphate (Disodium pyrophosphate), a food additive, is an inorganic compound. Sodium pyrophosphate has potential hematotoxic and immunotoxic effects[1].

In Vivo

Disodium pyrophosphate (oral administration, 12.6 mg/kg) displays hematotoxic and immunotoxic effects with long-term exposure in rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Adult Sprague-Dawley rats[1]
Dosage: 12.6 mg/kg
Administration: Oral administration
Result: Displayed significant leukopenic condition.
Decreased in CD3 T-lymphocyte and CD20 Blymphocyte immunolabeling in rats.
Downregulated of PPAR-α and PPAR-γ together with upregulation of TNF-α.
Clinical Trial
Molecular Weight

221.94

Formula

H2Na2O7P2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[Na2H2P2O7]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (450.57 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.5057 mL 22.5286 mL 45.0572 mL
5 mM 0.9011 mL 4.5057 mL 9.0114 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

SDS (393 KB)

COA (244 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 4.5057 mL 22.5286 mL 45.0572 mL 112.6431 mL
5 mM 0.9011 mL 4.5057 mL 9.0114 mL 22.5286 mL
10 mM 0.4506 mL 2.2529 mL 4.5057 mL 11.2643 mL
15 mM 0.3004 mL 1.5019 mL 3.0038 mL 7.5095 mL
20 mM 0.2253 mL 1.1264 mL 2.2529 mL 5.6322 mL
25 mM 0.1802 mL 0.9011 mL 1.8023 mL 4.5057 mL
30 mM 0.1502 mL 0.7510 mL 1.5019 mL 3.7548 mL
40 mM 0.1126 mL 0.5632 mL 1.1264 mL 2.8161 mL
50 mM 0.0901 mL 0.4506 mL 0.9011 mL 2.2529 mL
60 mM 0.0751 mL 0.3755 mL 0.7510 mL 1.8774 mL
80 mM 0.0563 mL 0.2816 mL 0.5632 mL 1.4080 mL
100 mM 0.0451 mL 0.2253 mL 0.4506 mL 1.1264 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sodium pyrophosphate7758-16-9Disodium pyrophosphate Sodium acid pyrophosphate SAPPBiochemical Assay ReagentsFood additiveimmunehematotoxicimmunotoxicInhibitorinhibitorinhibit

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