Sofinicline benzenesulfonate (Synonyms: ABT 894 benzenesulfonate)

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Sofinicline benzenesulfonate (ABT 894 benzenesulfonate) is a novel nicotinic acetylcholine receptor agonist, specifically acting on the α4β2 subtype of nAChR (IC₅₀=0.1 nM). Sofinicline benzenesulfonate has the potential to improve cognitive function, including attention, memory and working memory. Sofinicline benzenesulfonate can be used in studies of attention deficit, hyperactivity disorder (ADHD).

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Sofinicline benzenesulfonate Chemical Structure

CAS No. : 876170-44-4

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Other In-stock Forms of Sofinicline benzenesulfonate:

Sofiniclin

Other Forms of Sofinicline benzenesulfonate:

Sofiniclin In-stock

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Description	Sofinicline benzenesulfonate (ABT 894 benzenesulfonate) is a novel nicotinic acetylcholine receptor agonist, specifically acting on the α4β2 subtype of nAChR (IC₅₀=0.1 nM). Sofinicline benzenesulfonate has the potential to improve cognitive function, including attention, memory and working memory. Sofinicline benzenesulfonate can be used in studies of attention deficit, hyperactivity disorder (ADHD)^[1].
Molecular Weight	402.30
Formula	C₁₆H₁₇Cl₂N₃O₃S
CAS No.	876170-44-4
SMILES	O=S(O)(C1=CC=CC=C1)=O.ClC2=CC(N3C[C@@]4([H])[C@@](NC4)([H])C3)=CN=C2Cl
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (272 KB) Handling Instructions (2659 KB)
References	[1]. Fleisher C, et al. Sofinicline: a novel nicotinic acetylcholine receptor agonist in the treatment of attention-deficit/hyperactivity disorder[J]. Expert opinion on investigational drugs, 2014, 23(8): 1157-1163. [Content Brief]

Sofinicline benzenesulfonate Related Classifications

Neurological Disease

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sofinicline876170-44-4ABT 894ABT894ABT-894nAChRNicotinic acetylcholine receptorsAcetylcholine receptorssubtypesagonistsADHDcognitive functionInhibitorinhibitorinhibit

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Sofinicline benzenesulfonate (Synonyms: ABT 894 benzenesulfonate)

Other Forms of Sofinicline benzenesulfonate:

Sofinicline benzenesulfonate Related Antibodies

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