Sofpironium tosylate (Synonyms: BBI-4000 tosylate)

Cat. No.: HY-167849: FAQs
Data Sheet Handling Instructions

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Sofpironium (BBI 4000) tosylate is an anticholinergic agent used in the study of primary axillary hyperhidrosis (PAH). Sofpironium tosylate reduces sweating by inhibiting M3 muscarinic receptors in eccrine glands at the application site. Sofpironium tosylate also has a high afnity for the M1, M2, M4 and M5 subtypes.

For research use only. We do not sell to patients.

Sofpironium tosylate Chemical Structure

CAS No. : 2409055-48-5

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Other Forms of Sofpironium tosylate:

Sofpironium bromide Get quote

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mAChR1 mAChR2 mAChR3 mAChR4 mAChR5

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Description

IC₅₀ & Target

mAChR1

mAChR2

mAChR3

mAChR4

mAChR5

Molecular Weight

561.69

Formula

C₂₉H₃₉NO₈S

CAS No.

2409055-48-5

SMILES

O=S([O-])(C1=CC=C(C=C1)C)=O.CCOC(C[N+](C)(CC2)C[C@@H]2OC([C@@](C3CCCC3)(C4=CC=CC=C4)O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Julia Paik, et al. Sofpironium Bromide: First Approval. Drugs. 2020 Dec;80(18):1981-1986. [Content Brief]

Sofpironium tosylate Related Classifications

Neurological Disease

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sofpironium2409055-48-5BBI-4000BBI4000BBI 4000mAChRMuscarinic acetylcholine receptorhyperhidrosisanticholinergicM3muscarinicCYP2D6CYP3A4Inhibitorinhibitorinhibit

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