1. Others GPCR/G Protein Neuronal Signaling
  2. Isotope-Labeled Compounds mAChR
  3. Solifenacin-d7 hydrochloride

Solifenacin-d7 (hydrochloride) is the deuterium labeled Solifenacin hydrochloride. Solifenacin hydrochloride (YM905 hydrochloride) is a muscarinic receptor antagonist, with pKis of 7.6, 6.9 and 8.0 for M1, M2 and M3 receptors, respectively.

For research use only. We do not sell to patients.

Solifenacin-d<sub>7</sub> hydrochloride Chemical Structure

Solifenacin-d7 hydrochloride Chemical Structure

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Description

Solifenacin-d7 (hydrochloride) is the deuterium labeled Solifenacin hydrochloride. Solifenacin hydrochloride (YM905 hydrochloride) is a muscarinic receptor antagonist, with pKis of 7.6, 6.9 and 8.0 for M1, M2 and M3 receptors, respectively.

IC50 & Target

mAChR2

 

mAChR1

 

mAChR3

 

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

405.97

Formula

C23H20D7ClN2O2

Unlabeled CAS

180468-39-7

SMILES

O=C(O[C@]1([2H])C([2H])([2H])N2C([2H])([2H])CC1CC2([2H])[2H])N3[C@H](C4=C(CC3)C=CC=C4)C5=CC=CC=C5.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Solifenacin-d7 hydrochloride
Cat. No.:
HY-I0230S
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