2. Autophagy MAPK/ERK Pathway Apoptosis
  3. Ferroptosis Autophagy Apoptosis JNK
  4. SP 600125, negative control

SP 600125, negative control  (Synonyms: JNK Inhibitor II, negative control)

Cat. No.: HY-112402 Purity: 98.05%
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Handling Instructions Technical Support

SP 600125, negative control (SPM1) is an alkyl derivative of pyrazoloanthrone, which can be used as a negative control for SP600125 (HY-12041).

For research use only. We do not sell to patients.

SP 600125, negative control Chemical Structure

SP 600125, negative control Chemical Structure

CAS No. : 54642-23-8

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Based on 1 publication(s) in Google Scholar

SP 600125, negative control Related Antibodies

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Description

SP 600125, negative control (SPM1) is an alkyl derivative of pyrazoloanthrone, which can be used as a negative control for SP600125 (HY-12041)[1].

Molecular Weight

234.26

Formula

C15H10N2O
CAS No.
Appearance

Solid

Color

Yellow to orange

SMILES

O=C1C2=C3C(N(C)N=C3C4=CC=CC=C14)=CC=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (42.69 mM; ultrasonic and warming and heat to 70°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.2688 mL 21.3440 mL 42.6880 mL
5 mM 0.8538 mL 4.2688 mL 8.5376 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.2688 mL 21.3440 mL 42.6880 mL 106.7199 mL
5 mM 0.8538 mL 4.2688 mL 8.5376 mL 21.3440 mL
10 mM 0.4269 mL 2.1344 mL 4.2688 mL 10.6720 mL
15 mM 0.2846 mL 1.4229 mL 2.8459 mL 7.1147 mL
20 mM 0.2134 mL 1.0672 mL 2.1344 mL 5.3360 mL
25 mM 0.1708 mL 0.8538 mL 1.7075 mL 4.2688 mL
30 mM 0.1423 mL 0.7115 mL 1.4229 mL 3.5573 mL
40 mM 0.1067 mL 0.5336 mL 1.0672 mL 2.6680 mL
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SP 600125, negative control Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SP 600125, negative control54642-23-8JNK Inhibitor II, negative controlFerroptosisAutophagyApoptosisJNKc-Jun N-terminal kinaseInhibitorinhibitorinhibit

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