2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. Spermine(N3BBB)

Spermine(N3BBB) is a click chemistry reagent containing an azide group and can be used for various biochemical studies. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

For research use only. We do not sell to patients.

Spermine(N3BBB) Chemical Structure

Spermine(N3BBB) Chemical Structure

CAS No. : 1190203-80-5

Size Price Stock Quantity
5 mg USD 50 In-stock
10 mg USD 75 In-stock
25 mg USD 150 In-stock
50 mg USD 250 In-stock
100 mg USD 380 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Spermine(N3BBB) Related Antibodies

Top Publications Citing Use of Products

View All ADC Linker Isoform Specific Products:

View All Isoforms
Cleavable Linker Non-cleavable Linker Acid Cleavable Linker Disulfide Cleavable Linker Protease Cleavable Linker Glycosidase Cleavable Linker Phosphatase Cleavable Linker

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Spermine(N3BBB) is a click chemistry reagent containing an azide group and can be used for various biochemical studies[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Molecular Weight

528.69

Formula

C25H48N6O6
CAS No.
Appearance

Oil

Color

Colorless to light yellow

SMILES

[N-]=[N+]=NCCCN(CCCCN(CCCNC(OC(C)(C)C)=O)C(OC(C)(C)C)=O)C(OC(C)(C)C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (472.87 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8915 mL 9.4573 mL 18.9147 mL
5 mM 0.3783 mL 1.8915 mL 3.7829 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8915 mL 9.4573 mL 18.9147 mL 47.2867 mL
5 mM 0.3783 mL 1.8915 mL 3.7829 mL 9.4573 mL
10 mM 0.1891 mL 0.9457 mL 1.8915 mL 4.7287 mL
15 mM 0.1261 mL 0.6305 mL 1.2610 mL 3.1524 mL
20 mM 0.0946 mL 0.4729 mL 0.9457 mL 2.3643 mL
25 mM 0.0757 mL 0.3783 mL 0.7566 mL 1.8915 mL
30 mM 0.0630 mL 0.3152 mL 0.6305 mL 1.5762 mL
40 mM 0.0473 mL 0.2364 mL 0.4729 mL 1.1822 mL
50 mM 0.0378 mL 0.1891 mL 0.3783 mL 0.9457 mL
60 mM 0.0315 mL 0.1576 mL 0.3152 mL 0.7881 mL
80 mM 0.0236 mL 0.1182 mL 0.2364 mL 0.5911 mL
100 mM 0.0189 mL 0.0946 mL 0.1891 mL 0.4729 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Spermine(N3BBB) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Spermine(N3BBB)1190203-80-5ADC LinkerAntibody-drug conjugates linkerclick chemistryreagentazidebiochemicalInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Spermine(N3BBB)
Cat. No.:
HY-151657
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (252 KB) Français - FR (252 KB) Deutsch - DE (252 KB) Norwegian - NO (252 KB) Español - ES (252 KB) Swedish - SV (252 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.