Spexin TFA (Synonyms: Neuropeptide Q TFA)

Cat. No.: HY-P1723A: FAQs
Data Sheet Handling Instructions

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Spexin TFA is a potent galanin receptor 2/3 (GAL2/GAL3) agonist (EC₅₀ values are 45.7 and 112.2 nM, respectively). Spexin TFA exhibits no significant activity at galanin receptor 1. Spexin TFA is an endogenous satiety-inducing peptide; Spexin TFA inhibits long chain fatty acid uptake by adipocytes and decreases food consumption in diet-induced obese mice and rats. Spexin TFA attenuates LH secretion in goldfish. Spexin TFA exhibits anxiolytic effects in vivo.

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Spexin TFA Chemical Structure

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Other Forms of Spexin TFA:

Spexin Get quote

1 Publications Citing Use of MCE Spexin TFA

•Br J Pharmacol. 2024 Jul 3. [Abstract]

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NPY Y₁ receptor NPY Y₂ receptor NPY Y₄ receptor NPY Y₅ receptor

Biological Activity
Purity & Documentation
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Description	Spexin TFA is a potent galanin receptor 2/3 (GAL2/GAL3) agonist (EC₅₀ values are 45.7 and 112.2 nM, respectively). Spexin TFA exhibits no significant activity at galanin receptor 1. Spexin TFA is an endogenous satiety-inducing peptide; Spexin TFA inhibits long chain fatty acid uptake by adipocytes and decreases food consumption in diet-induced obese mice and rats. Spexin TFA attenuates LH secretion in goldfish. Spexin TFA exhibits anxiolytic effects in vivo.
Molecular Weight	1619.88 (free base)
Formula	C₇₄H₁₁₄N₂₀O₁₉S.xC₂HF₃O₂
Sequence Shortening	NWTPQAMLYLKGAQ-NH2
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (237 KB) Handling Instructions (2659 KB)

Spexin TFA Related Classifications

Metabolic Disease

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SpexinNeuropeptide QNeuropeptide Y ReceptorNPY receptorInhibitorinhibitorinhibit

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