2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor Autophagy
  3. Mineralocorticoid Receptor Androgen Receptor Autophagy
  4. Spironolactone (Standard)

Spironolactone (Standard)  (Synonyms: SC9420 (Standard))

Cat. No.: HY-B0561R Purity: ≥98%
Handling Instructions

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Spironolactone (Standard) is the analytical standard of Spironolactone. This product is intended for research and analytical applications. Spironolactone (SC9420) is an orally active aldosterone mineralocorticoid receptor antagonist with an IC50 of 24 nM. Spironolactone is also a potent antagonist of androgen receptor with an IC50 of 77 nM. Spironolactone promotes autophagy in podocytes.

For research use only. We do not sell to patients.

Spironolactone (Standard) Chemical Structure

Spironolactone (Standard) Chemical Structure

CAS No. : 52-01-7

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25 mg USD 96 In-stock
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100 mg USD 220 In-stock
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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

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Description
Molecular Weight

416.57

Formula

C₂₄H₃₂O₄S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@](OC3=O)(CC3)CC[C@@]1([H])[C@@]([C@@H](CC4=CC5=O)SC(C)=O)([H])[C@]([C@]4(CC5)C)([H])CC2
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Spironolactone (Standard) Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Spironolactone (Standard)52-01-7SC9420 (Standard)Mineralocorticoid ReceptorAndrogen ReceptorAutophagyInhibitorinhibitorinhibit

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