Stalk peptide

Cat. No.: HY-P10430: Data Sheet Handling Instructions Technical Support

Stalk peptide is a GPR110 activator. Stalk peptide is released from GPCR Autoproteolysis INducing domain by autocatalytic process and then Stalk peptide is inserted into the ligand-binding pocket of the receptor to activate the receptor. Stalk peptide can promote nerve growth and synaptic formation. Stalk peptide can be used to study neurodevelopmental and neurodegenerative diseases.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Stalk peptide Chemical Structure

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Description	Stalk peptide is a GPR110 activator. Stalk peptide is released from GPCR Autoproteolysis INducing domain by autocatalytic process and then Stalk peptide is inserted into the ligand-binding pocket of the receptor to activate the receptor. Stalk peptide can promote nerve growth and synaptic formation. Stalk peptide can be used to study neurodevelopmental and neurodegenerative diseases^[1].
Molecular Weight	1096.25
Formula	C₄₈H₇₇N₁₁O₁₆S
Sequence	Thr-Ser-Phe-Ser-Ile-Leu-Met-Ser-Pro-Asn
Sequence Shortening	TSFSILMSPN
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (256 KB) Handling Instructions (2659 KB)
References	[1]. Zhu X, et al. Structural basis of adhesion GPCR GPR110 activation by stalk peptide and G-proteins coupling[J]. Nature Communications, 2022, 13(1): 5513. [Content Brief]

Stalk peptide Related Classifications

Neurological Disease

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Keywords:

Stalk peptideTransmembrane GlycoproteinActivatorpeptidesautocatalysisNeurodegenerative diseasesNeurodevelopmentInhibitorinhibitorinhibit

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Stalk peptide

Featured Recommendations

•Related Small Molecules:

Biological Activity

Purity & Documentation

References

Customer Review

Stalk peptide Related Classifications

Molarity Calculator

Dilution Calculator