1. Immunology/Inflammation
  2. STING
  3. STING-IN-10

STING-IN-10 (P8) is a dual STING degrader and inhibitor with a DC50 value of 2.58 μM in THP-1 cells. STING-IN-10 has anti-inflammatory activity.

For research use only. We do not sell to patients.

STING-IN-10 Chemical Structure

STING-IN-10 Chemical Structure

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Description

STING-IN-10 (P8) is a dual STING degrader and inhibitor with a DC50 value of 2.58 μM in THP-1 cells. STING-IN-10 has anti-inflammatory activity[1].

Molecular Weight

727.68

Formula

C35H33N7O11

SMILES

O=C1CCC(C(N1)=O)N2C(C3=CC=CC(OCC4=CN(N=N4)CCCCCC(OCCC5=CC=C(C=C5)NC(C6=CC=C(O6)[N+]([O-])=O)=O)=O)=C3C2=O)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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STING-IN-10 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
STING-IN-10
Cat. No.:
HY-168554
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