2. Immunology/Inflammation
  3. STING
  4. STING modulator-3

STING modulator-3 is a STING inhibitor. STING modulator-3 inhibits R232 STING with an Ki value of 43.1 nM in scintillation proximity assay. STING modulator-3 has no effect on IRF-3 activation or TNF-β induction in THP-1 cells.

For research use only. We do not sell to patients.

STING modulator-3 Chemical Structure

STING modulator-3 Chemical Structure

CAS No. : 2839639-94-8

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STING modulator-3 Related Antibodies

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Description

STING modulator-3 is a STING inhibitor. STING modulator-3 inhibits R232 STING with an Ki value of 43.1 nM in scintillation proximity assay. STING modulator-3 has no effect on IRF-3 activation or TNF-β induction in THP-1 cells[1].

In Vitro

STING modulator-3 (AIP01) (10 μM; 3 h or 24 h) has no effect on phosphorylation of IRF-3 at 3 h, or on induction of TNF-β at 24 h in THP-1 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

STING modulator-3 Related Antibodies
Molecular Weight

375.39

Formula

C18H17N9O
CAS No.
SMILES

N#CCN1N=C(C)C=C1C2=CN(C)C(C3=NC(C(N)=O)=CC4=C3C=NN4C)=N2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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STING modulator-3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

STING modulator-32839639-94-8STING modulator3STING modulator 3STINGStimulator of Interferon GenesTMEM173MITAERISMPYSInhibitorinhibitorinhibit

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STING modulator-3
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HY-148606
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