Succinamic acid

Cat. No.: HY-W037980: FAQs
Data Sheet Handling Instructions

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Succinamic acid is a weak inhibitor for human LL-xylose reductase with an IC₅₀ of 1.45 mM. Succinamic acid can be used as a linker for synthesis of CQ-16 (HY-169336).

For research use only. We do not sell to patients.

Succinamic acid Chemical Structure

CAS No. : 638-32-4

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Description

Succinamic acid is a weak inhibitor for human LL-xylose reductase with an IC₅₀ of 1.45 mM. Succinamic acid can be used as a linker for synthesis of CQ-16 (HY-169336)^[1]^[2].

Molecular Weight

117.10

Formula

C₄H₇NO₃

CAS No.

638-32-4

Appearance

Solid

Color

White to off-white

SMILES

O=C(O)CCC(N)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature 3 years

In solvent	-80°C	2 years
	-20°C	1 year

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Carbone V, et al., Structure-based discovery of human L-xylulose reductase inhibitors from database screening and molecular docking. Bioorg Med Chem. 2005 Jan 17;13(2):301-12. [Content Brief]

[2]. Chen Q, et al., A Prostate-Specific Membrane Antigen-Targeting Small Molecule-Drug Conjugate Strategy to Overcome the Hematological Toxicity of Olaparib. J Med Chem. 2024 Nov 14;67(21):19586-19611. [Content Brief]

Succinamic acid Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Succinamic acid638-32-4PROTAC Linkersdiabetes mellitusInhibitorinhibitorinhibit

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