Suffruticosol A 

Suffruticosol A is a neuroprotective agent that restores scopolamine-induced cellular neurodegenerative damage. Suffruticosol A ameliorates hippocampal cholinergic deficits and partially enhances BDNF signaling. Suffruticosol A has neuromodulatory effects in a Scopolamine (HY-N0296)-induced model, restoring memory and cognitive performance in mice. Suffruticosol A can be isolated from seeds of P. lactiflora^[1].

BDNF^[1]

Suffruticosol A (20 μM; 24 h) recovers cell viability and survival on human neuroblastoma SH-SY5Y cells against Scopolamine treatment (2 mM)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Suffruticosol A (4 or 15 ng, twice a week; injected into third ventricle of the brain) improves neuronal effects in Scopolamine (1.0 mg/kg; ip) induced impairments of cognition and memory in mouse model^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

682.71

C₄₂H₃₄O₉

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Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Kim JH, et al. Enhanced neuronal activity by suffruticosol A extracted from Paeonia lactiflora via partly BDNF signaling in scopolamine-induced memory-impaired mice. Sci Rep. 2023 Jul 20;13(1):11731.  [Content Brief]