1. Neuronal Signaling Stem Cell/Wnt
  2. γ-secretase
  3. Sulindac sulfide-d3

Sulindac sulfide-d3  (Synonyms: cis-Sulindac sulfide-d3)

Cat. No.: HY-B1786S
Handling Instructions

Sulindac sulfide-d3 is deuterium labeled Sulindac sulfide. Sulindac sulfide is a noncompetitive γ-secretase inhibitor, with an IC50 of 20.2 μM for γ42-secretase activity.

For research use only. We do not sell to patients.

Sulindac sulfide-d<sub>3</sub> Chemical Structure

Sulindac sulfide-d3 Chemical Structure

CAS No. : 250608-66-3

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Description

Sulindac sulfide-d3 is deuterium labeled Sulindac sulfide. Sulindac sulfide is a noncompetitive γ-secretase inhibitor, with an IC50 of 20.2 μM for γ42-secretase activity.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

343.43

Formula

C20H14D3FO2S

CAS No.
Unlabeled CAS

49627-27-2

SMILES

OC(CC1=C(C)/C(C2=CC=C(F)C=C21)=C/C3=CC=C(C=C3)SC([2H])([2H])[2H])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Sulindac sulfide-d3
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