2. PI3K/Akt/mTOR
  3. PIN1
  4. TAB29

TAB29 is a potent inhibitor of peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) with an IC50 of 874 nM, possesses therapeutic potential for human cancers.

For research use only. We do not sell to patients.

TAB29 Chemical Structure

TAB29 Chemical Structure

CAS No. : 2361144-71-8

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TAB29 Related Antibodies

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Description

TAB29 is a potent inhibitor of peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) with an IC50 of 874 nM, possesses therapeutic potential for human cancers[1].

IC50 & Target

IC50：874 nM (Pin1)[1]
Cellular Effect
Cell Line Type Value Description References
SK-HEP1 IC50
1.14 μM
Compound: TAB29
Cytotoxicity against human SKHEP1 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against human SKHEP1 cells assessed as reduction in cell viability by MTT assay
[PMID: 31027708]
SNU-423 IC50
2.732 μM
Compound: TAB29
Cytotoxicity against human SNU423 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against human SNU423 cells assessed as reduction in cell viability by MTT assay
[PMID: 31027708]
Molecular Weight

406.47

Formula

C28H22O3
CAS No.
SMILES

C1(OCC2=CC=CC=C2)=CC(OCC3=CC=CC=C3)=C4C(OC=C4C5=CC=CC=C5)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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TAB29 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TAB292361144-71-8TAB 29TAB-29PIN1peptidylprolyl cis/trans isomerase, NIMA-interacting 1Inhibitorinhibitorinhibit

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HY-128592
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