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  4. TAS2R14 agonist-1

TAS2R14 agonist is a potent TAS2R14 partial agonist with an EC50 of 116.6 ±23.6 nM.

For research use only. We do not sell to patients.

TAS2R14 agonist-1 Chemical Structure

TAS2R14 agonist-1 Chemical Structure

CAS No. : 2439115-08-7

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TAS2R14 agonist-1 Related Antibodies

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Description

TAS2R14 agonist is a potent TAS2R14 partial agonist with an EC50 of 116.6 ±23.6 nM[1].

IC50 & Target

IC50: 116.6 nM (TAS2R14)[1]
In Vitro

In IP1 and cAMP assays, TAS2R14 agonist induce TAS2R14 activation with EC50 values of 100 nM and 180 nM about IP1 and cAMP accumulation, respectively.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

TAS2R14 agonist-1 Related Antibodies
Molecular Weight

373.26

Formula

C15H9F6N5
CAS No.
SMILES

FC(C1=CC(C(F)(F)F)=CC(NC2=CC=CC=C2C3=NNN=N3)=C1)(F)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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TAS2R14 agonist-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TAS2R14 agonist-12439115-08-7OthersBioisosteric replacementBitter taste receptorDrug designGPCRsStructure-based modelingflufenamic acidInhibitorinhibitorinhibit

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