2. GPCR/G Protein
  3. LPL Receptor
  4. TASP0277308

TASP0277308 is a highly selective S1P1 antagonist. TASP0277308 possesses immunomodulatory activities, including lymphopenia, a block in T cell egress from the thymus, marginal zone B cell displacement, and the upregulation of CD69 expression on lymphocytes. TASP0277308 can be used for the research of collagen-induced arthritis in mice.

For research use only. We do not sell to patients.

TASP0277308 Chemical Structure

TASP0277308 Chemical Structure

CAS No. : 945725-50-8

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TASP0277308 Related Antibodies

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Description

TASP0277308 is a highly selective S1P1 antagonist. TASP0277308 possesses immunomodulatory activities, including lymphopenia, a block in T cell egress from the thymus, marginal zone B cell displacement, and the upregulation of CD69 expression on lymphocytes. TASP0277308 can be used for the research of collagen-induced arthritis in mice[1].

Molecular Weight

539.48

Formula

C23H28Cl2N6O3S
CAS No.
SMILES

CCN1C(OC2=CC(N3CCN(CC3)C)=CC=C2)=NN=C1[C@@H](C)NS(=O)(C4=CC(Cl)=C(C=C4)Cl)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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TASP0277308 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TASP0277308945725-50-8TASP 0277308TASP-0277308LPL ReceptorLysophospholipid ReceptorS1PimmunomodulatoryCD69B cellT celllymphocytescollagen-induced arthritisInhibitorinhibitorinhibit

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